ArticleJournal of health, population, and nutrition2022
Activity of erythrocyte antioxidant enzymes in healthy women depends on age, BMI, physical activity, and diet.
Article in Journal of health, population, and nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Elemental analysis in menstrual effluent of women with PCOS: association with oxidative stress mechanisms: a case-control study.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- Oxidative stress and antioxidant enzyme activities in elite female Turkish cross-country skiers.BMC sports science, medicine & rehabilitation · 2026Article
- Nutritional Strategies and Aging: Current Evidence and Future Directions.Molecules (Basel, Switzerland) · 2026Review
- Antioxidants in cancer therapy mitigating lipid peroxidation without compromising treatment through nanotechnology.Discover nano · 2025Review
- Dietary exposure to di(2-ethylhexyl) phthalate for 6 months alters markers of female reproductive aging in mice†.Biology of reproduction · 2025Article
- The Effects of Physical Activity on Skin Health: A Narrative Review.Clinical, cosmetic and investigational dermatology · 2025Review
- Investigation of Antioxidant Enzymes (GST, GSH, R-GSSG) in Erythrocytes of COVID-19 Patients: A One-Month Observation.Journal of inflammation research · 2025Article
- Article
- Temporal variation in production performance, biochemical and oxidative stress markers, and gut microbiota in Pekin ducks during the late growth stage.Poultry science · 2024Article
- Significant Increase in Oxidative Stress Indices in Erythrocyte Membranes of Obese Patients with Metabolically-Associated Fatty Liver Disease.Journal of personalized medicine · 2024Article
- Serum trace element levels and activity of enzymes associated with oxidative stress in endometriosis and endometrial cancer.FEBS open bio · 2024Article
- Reactive Oxygen Species: A Crosslink between Plant and Human Eukaryotic Cell Systems.International journal of molecular sciences · 2023Review
- The Influence of Circadian Rhythm on the Activity of Oxidative Stress Enzymes.International journal of molecular sciences · 2022Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAntioxidant enzymes protect the human body against the harmful effects of oxidative stress. The activity of antioxidant enzymes changes with age and depends on dietary nutrients such as fats and vitamins, which can have a significant impact on minimizing or exacerbating oxidative stress.
aimTo examine the effect of age, BMI, diet, physical activity, and smoking status on the activity of erythrocyte antioxidant enzymes catalase, glutathione reductase, glutathione peroxidase glutathione S-transferase, superoxide dismutase, and glutathione concentrations in healthy women. MATERIAL AND
methodsThis study included 98 healthy women aged between 20 and 65 years. All women underwent anthropometric tests: body weight, height, hip, and waist circumference. Antioxidant activity in erythrocytes was measured by spectrophotometric methods.
resultsCatalase activity increased significantly with age (p < 0.001), while superoxide dismutase activities and glutathione decreased with age (p = 0.008, p = 0.023, respectively). Women with a lower BMI (emaciation) had higher superoxide dismutase activity than those in the first degree of obesity (p = 0.009).
conclusions(1) Increased catalase activity with age may signify a large amount of hydrogen peroxide resulting from malfunctioning antioxidant systems in old age. (2) A decline in superoxide dismutase activity with age may indicate inactivation of this enzyme, inappropriate SOD function in the presence of excessive amounts of hydrogen peroxide, and glycation of superoxide dismutase molecules. (3) A negative correlation between superoxide dismutase activity and the BMI index may indicate a decreased enzymatic activity in obese people.
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