Evidence map›Paper›PMID 35978377›Full record

ArticleTrials2022

Integrated traditional Chinese medicine intervention for delaying HIV morbidity: study protocol for a multicentre randomised controlled trial.

Xue Ding, Pengfei Meng, Xiuxia Ma, Weifeng Cui, Liangping Li, Xiyuan Song, Jiangrong Wang, Chengjie Ma, Xin Chen, Liran Xu

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Xue DingThe First Affiliated Hospital of Henan University of Chinese Medicine, 19 Renmin Road, Zhengzhou, 450099, China.
Pengfei MengThe First Affiliated Hospital of Henan University of Chinese Medicine, 19 Renmin Road, Zhengzhou, 450099, China.
Xiuxia MaThe First Affiliated Hospital of Henan University of Chinese Medicine, 19 Renmin Road, Zhengzhou, 450099, China.
Weifeng CuiThe Affiliated Hospital of Henan Academy of Chinese Medicine, Zhengzhou, 450004, China.
Liangping LiThe First Affiliated Hospital of Henan University of Chinese Medicine, 19 Renmin Road, Zhengzhou, 450099, China.
Xiyuan SongThe First Affiliated Hospital of Henan University of Chinese Medicine, 19 Renmin Road, Zhengzhou, 450099, China.
Jiangrong WangShanghai Public Health Clinical Centre, Shanghai, 200000, China.
Chengjie MaBeijing Ditan Hospital Capital Medical University, Beijing, 100000, China.
Xin ChenKunming Municipal Hospital of Traditional Chinese Medicine, Kunming, 650000, China.
Liran XuThe First Affiliated Hospital of Henan University of Chinese Medicine, 19 Renmin Road, Zhengzhou, 450099, China. xuliran666@sina.com.ORCID http://orcid.org/0000-0002-3992-7423
First Affiliated Hospital of Henan University · CNCapital Medical University · CNKunming Municipal Hospital of Traditional Chinese Medicine · CNShanghai Public Health Clinical Center · CN

Funding

international science and technology cooperation programme No.2017ZX10205502national natural science foundation of china U1604287national natural science foundation of china U1904153
6 · The paper itself

Abstract

backgroundAcquired immune deficiency syndrome is caused by humans and is high worldwide. Active antiretroviral therapy emerged in the late 1990s and is effective against AIDS. However, despite the extensive research on AIDS, there is still no vaccine or cure. The benefits of traditional Chinese medicine (TCM) for AIDS are increasingly recognised, especially by patients with asymptomatic HIV infection. METHODS/

designThe proposed trial will enrol 216 eligible patients who will be randomised into treatment and control groups. After 72 weeks of intervention, the efficacy and safety of TCM for patients with AIDS will be assessed. The variables that will be measured include clinical symptoms, TCM syndromes, viral load, immunological indicators, inflammatory factors, quality of life, patient-reported outcomes and safety assessment. DISCUSSION: The study aim to compare the effectiveness and safety of TCM for asymptomatic AIDS and explore its potential underlying mechanism. Additionally, the findings will provide a reference for the use of TCM to delay the onset and control the progression of HIV/AIDS.

trial registrationChinese Clinical Trial Registry ChiCTR1800018365. Registered on 13 September 2018.

Indexed as

Acquired Immunodeficiency SyndromeDrugs, Chinese HerbalHIV InfectionsHumansMedicine, Chinese TraditionalMorbidityMulticenter Studies as TopicQuality of LifeRandomized Controlled Trials as TopicTreatment OutcomeDrugs, Chinese HerbalAIDSClinical trialsComplementary medicineHIV

Identifiers

PMID35978377
PMCPMC9386919
OpenAlexW4292266451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.