Evidence map›Paper›PMID 35978193›Full record

ArticleNature2022

In vivo single-molecule analysis reveals COOLAIR RNA structural diversity.

Minglei Yang, Pan Zhu, Jitender Cheema, Rebecca Bloomer, Pawel Mikulski, Qi Liu, Yueying Zhang, Caroline Dean, Yiliang Ding

Abstract read
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. RNA regulation in plants.Science China. Life sciences · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Optimized tRNA structure-seq reveals robust tRNA secondary structures inbioRxiv : the preprint server for biology · 2026
    Article
  20. Review

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Minglei Yang *John Innes Centre, Norwich Research Park, Norwich, UK.
Pan Zhu *John Innes Centre, Norwich Research Park, Norwich, UK.ORCID http://orcid.org/0000-0003-0029-3571
Jitender CheemaJohn Innes Centre, Norwich Research Park, Norwich, UK.
Rebecca BloomerJohn Innes Centre, Norwich Research Park, Norwich, UK.ORCID http://orcid.org/0000-0002-0902-1807
Pawel MikulskiJohn Innes Centre, Norwich Research Park, Norwich, UK.
Qi LiuJohn Innes Centre, Norwich Research Park, Norwich, UK.
Yueying ZhangJohn Innes Centre, Norwich Research Park, Norwich, UK.
Caroline DeanJohn Innes Centre, Norwich Research Park, Norwich, UK. caroline.dean@jic.ac.uk.ORCID http://orcid.org/0000-0002-6555-3525
Yiliang DingJohn Innes Centre, Norwich Research Park, Norwich, UK. yiliang.ding@jic.ac.uk.ORCID http://orcid.org/0000-0003-4161-6365

Funding

Biotechnology and Biological Sciences Research Council BBS/E/J/000PR9773Biotechnology and Biological Sciences Research Council BBS/E/J/000PR9788European Research Council 680324Wellcome Trust 210654Wellcome Trust 210654/Z/18/Z
6 · The paper itself

Abstract

Cellular RNAs are heterogeneous with respect to their alternative processing and secondary structures, but the functional importance of this complexity is still poorly understood. A set of alternatively processed antisense non-coding transcripts, which are collectively called COOLAIR, are generated at the Arabidopsis floral-repressor locus FLOWERING LOCUS C (FLC)

Indexed as

ArabidopsisNucleic Acid ConformationRNA, AntisenseRNA, PlantRNA, UntranslatedSingle Molecule ImagingArabidopsis ProteinsFlowersGene Expression Regulation, PlantMADS Domain ProteinsTranscription, GeneticTranscription Initiation SiteArabidopsis ProteinsAt5g10140 protein, ArabidopsisMADS Domain ProteinsRNA, AntisenseRNA, PlantRNA, Untranslated

Identifiers

PMID35978193
PMCPMC9452300

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.