Evidence map›Paper›PMID 35978111›Full record

Observational studyClinical research in cardiology : official journal of the German Cardiac Society2023

Effects of the COVID-19 pandemic on acute coronary syndromes in Germany during the first wave: the COVID-19 collateral damage study.

Uwe Zeymer, Vusal Ahmadli, Steffen Schneider, Karl Werdan, Michael Weber, Sven Hohenstein, Gerhard Hindricks, Steffen Desch, Andreas Bollmann, Holger Thiele

Open access · hybridAbstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Clinical research in cardiology : official journal of the German Cardiac Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Catheter based left atrial appendage closure in-hospital outcomes in Germany from 2016 to 2020.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Uwe ZeymerMedizinische Klinik B, Klinikum Ludwigshafen, Klinik für Innere Medizin/Kardiologie, Bremserstr. 79, 67063, Ludwigshafen, Germany. uwe.zeymer@t-online.de.
Vusal AhmadliDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Strümpellstraße 39, 04289, Leipzig, Germany.
Steffen SchneiderInstitut für Herzinfarktforschung, Ludwigshafen, Germany.
Karl WerdanDGK Zentrum für Kardiologische Versorgungsforschung, Düsseldorf, Germany.
Michael WeberVerband der Leitenden Krankenhausärzte Deutschlands e.V., Karlsruhe, Germany.
Sven HohensteinDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Strümpellstraße 39, 04289, Leipzig, Germany.
Gerhard HindricksLeipzig Heart Institute, Leipzig, Germany.
Steffen DeschDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Strümpellstraße 39, 04289, Leipzig, Germany.
Andreas BollmannLeipzig Heart Institute, Leipzig, Germany.
Holger ThieleDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Strümpellstraße 39, 04289, Leipzig, Germany. holger.thiele@medizin.uni-leipzig.de.ORCID http://orcid.org/0000-0002-0169-998X
Leipzig Heart Institute · DEStiftung Institut für Herzinfarktforschung · DEGerman Cardiac Society · DEGKV Spitzenverband · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReports about the influence of the COVID-19 pandemic on the number of hospital admissions and in-hospital mortality during the first wave between March and May 2020 showed conflicting results and are limited by single-center or limited regional multicenter datasets. Aim of this analysis covering all German federal states was the comprehensive description of hospital admissions and in-hospital mortality during the first wave of the COVID-19 pandemic. METHODS AND

resultsWe conducted an observational study on hospital routine data (§21 KHEntgG) and included patients with the main diagnosis of acute myocardial infarction (ICD 21 and ICD 22). A total of 159 hospitals included 36,329 patients in the database, with 12,497 patients admitted with ST-elevation myocardial infarction (STEMI) and 23,832 admitted with non-ST-elevation myocardial infarction (NSTEMI). There was a significant reduction in the number of patients admitted with STEMI (3748 in 2020, 4263 in 2019 and 4486 in 2018; p < 0.01) and NSTEMI (6957 in 2020, 8437 in 2019 and 8438 in 2020; p < 0.01). These reductions were different between the Federal states of Germany. Percutaneous coronary intervention was performed more often in 2020 than in 2019 (odds ratio 1.13, 95% confidence interval [CI] 1.06-1.21) and 2018 (odds ratio 1.20, 95% CI 1.12-1.29) in NSTEMI and more often than in 2018 (odds ratio 1.26, 95% CI 1.10-1.43) in STEMI. The in-hospital mortality did not differ between the years for STEMI and NSTEMI, respectively.

conclusionsIn this large representative sample size of hospitals in Germany, we observed significantly fewer admissions for NSTEMI and STEMI during the first COVID-19 wave, while quality of in-hospital care and in-hospital mortality were not affected. Admissions for STEMI and NSTEMI during the months March to May over 3 years and corresponding in-hospital mortality for patients with STEMI and NSTEMI in 159 German hospitals. (p-value for admissions 2020 versus 2019 and 2018: < 0.01; p-value for mortality: n.s.).

Indexed as

Acute Coronary SyndromeCOVID-19Non-ST Elevated Myocardial InfarctionPercutaneous Coronary InterventionST Elevation Myocardial InfarctionHumansPandemicsAcute myocardial infarctionCollateral damageCOVID-19 pandemicMortalityRevascularization

Identifiers

PMID35978111
PMCPMC9385100
OpenAlexW4292265396

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.