Evidence map›Paper›PMID 35978105›Full record

Observational studyJournal of perinatology : official journal of the California Perinatal Association2023

Human milk pH is associated with fortification, postpartum day, and maternal dietary intake in preterm mother-infant dyads.

Evgenia Jen Filatava, Colleen E Shelly, Nicolette E Overton, Matt Gregas, Robert Glynn, Katherine E Gregory

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Point-of-care human milk concentration by passive osmosis: comprehensive analysis of fresh human milk samples.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Evgenia Jen FilatavaBrigham and Women's Hospital, Boston, MA, USA.
Colleen E ShellyBoston College, Boston, MA, USA.
Nicolette E OvertonBrigham and Women's Hospital, Boston, MA, USA.
Matt GregasBoston College, Boston, MA, USA.
Robert GlynnBrigham and Women's Hospital, Boston, MA, USA.
Katherine E GregoryBrigham and Women's Hospital, Boston, MA, USA. gregorkc@bc.edu.ORCID 0000-0002-0610-5386
Boston College · USBrigham and Women's Hospital · US

Funding

The influence of the milk microbiome on inflammation of the preterm infantR21NR017256 · NINR · BRIGHAM AND WOMEN'S HOSPITAL · PI GREGORY, KATHERINE ELIZABETH · 2018 to 2019
$520k
NIH HHS R21NR017256NINR NIH HHS R21 NR017256
6 · The paper itself

Abstract

objectiveTo compare pH of human milk types (mother's own milk (MOM), pasteurized donor human milk (PDHM), fortified MOM, and fortified PDHM) fed to preterm infants. STUDY

designThis observational study consisted of 63 mother-infant dyads < 34 weeks gestation. Human milk samples (n = 245), along with maternal factors, were collected for pH analysis. pH of MOM was analyzed over the course of lactation accounting for fortification status, postpartum day, and storage conditions.

resultsMean pH of MOM was slightly acidic at 6.60 ± 0.28, which was significantly higher (p < 0.05) than other milk types. pH of MOM varied by fortification, postpartum day, and maternal vegetable/fiber intake. There was a significant interaction between fortification status and postpartum day; pH of MOM decreased over time, while pH of fortified MOM increased over time.

conclusionpH of human milk varied by type. pH of MOM was significantly associated with fortification status, postpartum day, and maternal vegetable/fiber intake.

Indexed as

Infant, PrematureMilk, HumanBreast FeedingEatingFemaleHumansHydrogen-Ion ConcentrationInfantInfant, NewbornLactationMothers

Identifiers

PMID35978105
PMCPMC9840648
OpenAlexW4292295465

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.