ArticleScientific reports2022
Association between prognostic factors and the clinical deterioration of preterm neonates with necrotizing enterocolitis.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.
- Association between packed red blood cell transfusion and clinical deterioration in neonatal necrotizing enterocolitis: a systematic review and meta-analysis.Annals of medicine · 2026Pooled it
- A meta-analysis on the predictive role of CRP in NEC diagnosis and prognosis.Italian journal of pediatrics · 2025Pooled it
- Validation of a Predictive Nomogram for Mortality Among Neonates With Necrotizing Enterocolitis in Tertiary Care Hospitals at Bahir Dar City, Bahir Dar, Northwest Ethiopia.Clinical medicine insights. Pediatrics · 2026Article
- Association between hypertensive disorders of pregnancy and disease progression in preterm infants with necrotizing enterocolitis: a retrospective cohort study.European journal of medical research · 2025Article
- Exploring the predictive value of pH in stratified mortality risk of NEC patients undergoing surgery: a retrospective study based on the PIC database.Translational pediatrics · 2025Article
- Diagnostic and Prognostic Value of Hematological Parameters in Necrotizing Enterocolitis: A Systematic Review.Journal of clinical medicine · 2025Review
- Adoption value of serum hematological inflammatory markers in early diagnosis of necrotising enterocolitis.Journal of medical biochemistry · 2025Article
- Rapidly progressive necrotizing enterocolitis: Risk factors and a predictive model.Pediatric research · 2025Article
- Gestational age-specific hematological features in preterm infants with necrotizing enterocolitis.Pediatric research · 2024Article
- C-Reactive Protein: Pathophysiology, Diagnosis, False Test Results and a Novel Diagnostic Algorithm for Clinicians.Diseases (Basel, Switzerland) · 2023Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Necrotizing enterocolitis (NEC) is responsible for most morbidity and mortality in neonates. Early recognition of the clinical deterioration in newborns with NEC is essential to enhance the referral and management and potentially improve the outcomes. Here, we aimed to identify the prognostic factors and associate them with the clinical deterioration of preterm neonates with NEC. We analyzed the medical records of neonates with NEC admitted to our hospital from 2016 to 2021. We ascertained 214 neonates with NEC. The area under the receiver operating characteristic (ROC) curve and cut-off level of age at onset, C-reactive protein (CRP), leukocyte count, and platelet count for the clinical deterioration of preterm neonates with NEC was 0.644 and 10.5 days old, 0.694 and 4.5 mg/L, 0.513 and 12,200/mm
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