ArticleScientific reports2022
Fitting of TC model according to key parameters affecting Parkinson's state based on improved particle swarm optimization algorithm.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biophysical models contain a large number of parameters, while the spiking characteristics of neurons are related to a few key parameters. For thalamic neurons, relay reliability is an important characteristic that affects Parkinson's state. This paper proposes a method to fit key parameters of the model based on the spiking characteristics of neurons, and improves the traditional particle swarm optimization algorithm. That is, a nonlinear concave function and a Logistic chaotic mapping are combined to adjust the inertia weight of particles to avoid the particle falling into a local optimum in the search process or appearing premature convergence. In this paper, three parameters that play an important role in Parkinson's state of the thalamic cell model are selected and fitted by the improved particle swarm optimization algorithm. Using the fitted parameters to reconstruct the neuron model can predict the spiking trajectories well, which verifies the effectiveness of the fitting method. By comparing the fitting results with other particle swarm optimization algorithms, it is shown that the proposed particle swarm optimization algorithm can better avoid local optima and converge to the optimal values quickly.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.