Evidence map›Paper›PMID 35977894›Full record

ArticleAcute and critical care2022

The role of diaphragmatic thickness measurement in weaning prediction and its comparison with rapid shallow breathing index: a single-center experience.

Lokesh Kumar Lalwani, Manjunath B Govindagoudar, Pawan Kumar Singh, Mukesh Sharma, Dhruva Chaudhry

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Article in Acute and critical care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

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6citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

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3 · Its place in the literature

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6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Lokesh Kumar LalwaniDepartment of Tuberculosis and Respiratory Medicine, Post Graduate Institute of Medical Sciences, Rohtak, India.
Manjunath B GovindagoudarDepartment of Pulmonary and Critical Care Medicine, Post Graduate Institute of Medical Sciences, Rohtak, India.
Pawan Kumar SinghDepartment of Pulmonary and Critical Care Medicine, Post Graduate Institute of Medical Sciences, Rohtak, India.
Mukesh SharmaChest and Bronchoscopy Centre, Agra, India.
Dhruva ChaudhryDepartment of Pulmonary and Critical Care Medicine, Post Graduate Institute of Medical Sciences, Rohtak, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute respiratory failure (ARF) is commonly managed with invasive mechanical ventilation (IMV). The majority of the time that a patient spends on IMV is in the process of weaning. Prediction of the weaning outcome is of paramount importance, as untimely/delayed extubation is associated with a high risk of mortality. Diaphragmatic ultrasonography is a promising tool in the intensive care unit, and its utility in predicting the success of weaning remains understudied.

methodsIn this prospective-observational study, we recruited 54 ARF patients on IMV, along with 50 healthy controls. During a spontaneous breathing trial, all subjects underwent diaphragmatic ultrasonography along with a rapid shallow breathing index (RSBI) assessment.

resultsThe mean age was 41.8±17.0 and 37.6±10.5 years among the cases and control group, respectively. Demographic variables were broadly similar in the two groups. The most common cause of ARF was obstructive airway disease. The average duration of IMV was 5.41±2.81 days. Out of 54 subjects, 45 were successfully weaned, while nine patients failed weaning. Age, body mass index, and severity of disease were similar in the successful and failed weaning patients. The sensitivity in predicting successful weaning of percent change in diaphragmatic thickness (Δtdi%) >29.71% was high (93.33%), while specificity was 66.67%. The sensitivity and specificity of mean diaphragmatic thickness (tdi) end-expiratory >0.178 cm was 60.00% and 77.78%, respectively. RSBI at 1 minute of <93.75 had an equally high sensitivity (93.33%) but a lower specificity (22.22%). Similar results were also found for RSBI measured at 5 minutes.

conclusionsDuring the weaning assessment, the purpose is to minimize both premature as well as delayed extubation. We found that diaphragmatic ultrasonography, in particular Δtdi%, is better than RSBI in predicting weaning outcomes.

Indexed as

artificial respirationdiaphragmrespiratory insufficiencyultrasoundventilator weaning

Identifiers

PMID35977894
PMCPMC9475163

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