ArticleAcute and critical care2022
Association between C-reactive protein-to-albumin ratio and 6-month mortality in out-of-hospital cardiac arrest.
Article in Acute and critical care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Association of Serial Lactate-to-Albumin and C-Reactive Protein-to-Albumin Ratios with In-Hospital Mortality After Out-of-Hospital Cardiac Arrest.Journal of clinical medicine · 2026Article
- C-reactive protein-to-albumin ratio as a novel prognostic biomarker for long-term mortality in pericarditis: a real-world study.BMC cardiovascular disorders · 2025Article
- C-reactive protein-to-albumin ratio is associated with mortality after transcatheter tricuspid valve repair.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Association of the blood urea nitrogen to serum albumin ratio and 28-day all-cause mortality in patients with cardiac arrest: a retrospective cohort study using the MIMIC-IV database.Frontiers in cardiovascular medicine · 2025Article
- Machine Learning and Clinical Predictors of Mortality in Cardiac Arrest Patients: A Comprehensive Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- The association between C-reactive protein to albumin ratio and 6-month neurological outcome in patients with in-hospital cardiac arrest.World journal of emergency medicine · 2024Article
- C-reactive protein-to-albumin ratio as a biomarker in patients with sepsis: a novel LASSO-COX based prognostic nomogram.Scientific reports · 2023Article
- Comparison of Prognostic Performance between Procalcitonin and Procalcitonin-to-Albumin Ratio in Post Cardiac Arrest Syndrome.Journal of clinical medicine · 2023Article
- Biomarkers in Cardiac Arrest: A Narrative Review.Therapeutic advances in pulmonary and critical care medicineReview
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe inflammatory response that occurs following cardiac arrest can determine the long-term prognosis of patients who survive out-of-hospital cardiac arrest. We evaluated the correlation between C-reactive protein-to-albumin ratio (CAR) following cardiac arrest and long-term mortality.
methodsThe current retrospective observational study examined patients with post-cardiac arrest syndrome (PCAS) treated with targeted temperature management at a single tertiary care hospital. We measured CAR at four time points (at admission and then 24 hours, 48 hours, and 72 hours after) following cardiac arrest. The primary outcome was the patients' 6-month mortality. We performed multivariable and area under the receiver operating characteristic curve (AUC) analyses to investigate the relationship between CAR and 6-month mortality.
resultsAmong the 115 patients, 52 (44.1%) died within 6 months. In the multivariable analysis, CAR at 48 hours (odds ratio [OR], 1.130; 95% confidence interval [CI], 1.027-1.244) and 72 hours (OR, 1.241; 95% CI, 1.059-1.455) after cardiac arrest was independently associated with 6-month mortality. The AUCs of CAR at admission and 24, 48, and 72 hours after cardiac arrest for predicting 6-month mortality were 0.583 (95% CI, 0.489-0.673), 0.622 (95% CI, 0.528-0.710), 0.706 (95% CI, 0.615-0.786), and 0.762 (95% CI, 0.675-0.835), respectively.
conclusionsCAR at 72 hours after cardiac arrest was an independent predictor for long-term mortality in patients with PCAS.
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