Evidence map›Paper›PMID 35977514›Full record

ArticleCell reports2022

Microglia contribute to the postnatal development of cortical somatostatin-positive inhibitory cells and to whisker-evoked cortical activity.

Lorenzo Gesuita, Anna Cavaccini, Ali Özgür Argunsah, Emilia Favuzzi, Leena Ali Ibrahim, Tevye Jason Stachniak, Martina De Gennaro, Sebastian Utz, Melanie Greter, Theofanis Karayannis

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 36 citations in OpenAlex.

  1. Microglia Modulate Information Processing in the Mouse Barrel Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Interneuron Diversity: How Form Becomes Function.Cold Spring Harbor perspectives in biology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Microglia and Microbiome-Gut-Brain Axis.Advances in neurobiology · 2024
    Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Lorenzo GesuitaLaboratory of Neural Circuit Assembly, Brain Research Institute, University of Zurich, Zurich 8057, Switzerland; Neuroscience Center Zurich (ZNZ), Zurich 8057, Switzerland.
Anna CavacciniLaboratory of Neural Circuit Assembly, Brain Research Institute, University of Zurich, Zurich 8057, Switzerland; Neuroscience Center Zurich (ZNZ), Zurich 8057, Switzerland.
Ali Özgür ArgunsahLaboratory of Neural Circuit Assembly, Brain Research Institute, University of Zurich, Zurich 8057, Switzerland; Neuroscience Center Zurich (ZNZ), Zurich 8057, Switzerland.
Emilia FavuzziDepartment of Neurobiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
Leena Ali IbrahimDepartment of Neurobiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
Tevye Jason StachniakLaboratory of Neural Circuit Assembly, Brain Research Institute, University of Zurich, Zurich 8057, Switzerland; Neuroscience Center Zurich (ZNZ), Zurich 8057, Switzerland.
Martina De GennaroLaboratory of Neural Circuit Assembly, Brain Research Institute, University of Zurich, Zurich 8057, Switzerland; Neuroscience Center Zurich (ZNZ), Zurich 8057, Switzerland.
Sebastian UtzInstitute of Experimental Immunology, University of Zurich, Zurich 8057, Switzerland.
Melanie GreterInstitute of Experimental Immunology, University of Zurich, Zurich 8057, Switzerland.
Theofanis KarayannisLaboratory of Neural Circuit Assembly, Brain Research Institute, University of Zurich, Zurich 8057, Switzerland; Neuroscience Center Zurich (ZNZ), Zurich 8057, Switzerland. Electronic address: karayannis@hifo.uzh.ch.
University of Zurich · CHBroad Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microglia play a key role in shaping the formation and refinement of the excitatory network of the brain. However, less is known about whether and how they organize the development of distinct inhibitory networks. We find that microglia are essential for the proper development of somatostatin-positive (SST

Indexed as

InterneuronsVibrissaeAnimalsMicrogliaSomatostatinSynapsesSomatostatincerebral cortexCP: Neurosciencedevelopmentinhibitory synapsesinterneuronsmicrogliasomatostatin

Identifiers

PMID35977514
PMCPMC9396528
OpenAlexW4292056106

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.