Evidence map›Paper›PMID 35977491›Full record

ArticleCell reports2022

Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.

Jory A Goldsmith, Andrea M DiVenere, Jennifer A Maynard, Jason S McLellan

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Covalently Linked Peptides and Membrane Potential Enable CyaA Segment Translocation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. The Minimal Folding Motif of the Repeat-in-Toxin Domain of Adenylate Cyclase Toxin.Langmuir : the ACS journal of surfaces and colloids · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. αStructure (London, England : 1993) · 2024
    Article
  13. Article
  14. Review
  15. αbioRxiv : the preprint server for biology · 2024
    Article
  16. CyaA translocation across eukaryotic cell membranes.Frontiers in molecular biosciences · 2024
    Article
  17. Family-wide analysis of integrin structures predicted by AlphaFold2.bioRxiv : the preprint server for biology · 2023
    Article
  18. Article
  19. Outsmarting Pathogens with Antibody Engineering.Annual review of chemical and biomolecular engineering · 2023
    Review
  20. Family-wide analysis of integrin structures predicted by AlphaFold2.Computational and structural biotechnology journal · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jory A GoldsmithDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA.
Andrea M DiVenereDepartment of Chemical Engineering, The University of Texas at Austin, Austin, TX 78712, USA.
Jennifer A MaynardDepartment of Chemical Engineering, The University of Texas at Austin, Austin, TX 78712, USA. Electronic address: maynard@che.utexas.edu.
Jason S McLellanDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA. Electronic address: jmclellan@austin.utexas.edu.
The University of Texas at Austin · US

Funding

Structure, function and antigenicity of B. pertussis virulence factorsR01AI155453 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI MAYNARD, JENNIFER A, MCLELLAN, JASON SCOTT · 2021 to 2025
$2.8M
NIAID NIH HHS R01 AI155453
6 · The paper itself

Abstract

Integrins are ubiquitous cell-surface heterodimers that are exploited by pathogens and toxins, including leukotoxins that target β

Indexed as

IntegrinsPhagocytesAdenylate Cyclase ToxinCD18 AntigensCryoelectron MicroscopyAdenylate Cyclase ToxinCD18 AntigensIntegrinsbacteriaCP: Microbiologycryo-EMhemolysinhost-pathogen interactionsintegrinsmembrane insertionreceptor bindingtoxintype I secretion system

Identifiers

PMID35977491
PMCPMC9416875
OpenAlexW4292056151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.