Observational studyCardiovascular journal of Africa
Association between bifurcation angle of the left main coronary artery and severity of stenosis of the proximal left anterior descending artery.
Observational study in Cardiovascular journal of Africa. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed, 3 citations in OpenAlex.
- A systematic review of left mainstem quadfurcation anatomy 'The Starfish Sign': an incidental finding or a variant of concern?European heart journal. Imaging methods and practice · 2026Review
- Association between the bifurcation angle and the angle of the origin of the left anterior descending with the severity of coronary artery disease.ARYA atherosclerosis · 2026Article
- Comprehensive Risk Assessment of LAD Disease Progression in CCTA: The CLAP Score Study.Journal of cardiovascular development and disease · 2024Article
- Predicting severe proximal left anterior descending coronary artery stenosis using proximal left anterior descending coronary artery tortuosity and the angle between the left main and anterior descending coronary arteries: a retrospective cross-sectional study.Quantitative imaging in medicine and surgery · 2023Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of this study was to evaluate the association between the left main coronary artery (LM) bifurcation angle and the severity of the proximal left anterior descending coronary artery (LAD) stenosis.
methodsTwo hundred patients with suspected coronary artery disease who had coronary angiography were included in this observational study. The severity of coronary artery stenosis was analysed using quantitative coronary angiography software (QCA analysis). The LM-LAD and LAD-left circumflex artery (LCX) angles were measured using software (IC MEASURE) in two-dimensional axial images.
resultsThe patients were divided into two groups. The first group included 100 patients with significant proximal LAD stenosis (≥ 50%) and the second, those with LAD stenosis < 50% (100 patients). Patients with significant proximal LAD stenosis were older and had a higher frequency of diabetes mellitus, and higher serum creatinine and low-density lipoprotein levels than those with non-significant LAD stenosis. The LM-LAD and LAD-LCX angles in patients with significant proximal LAD stenosis were wider than in patients with non-significant LAD stenosis (
conclusionsWider LM-LAD and LAD-LCX angles were associated with the severity of proximal LAD disease. Preventative measures and close follow up are needed in such cases to improve their cardiovascular outcome.
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