Evidence map›Paper›PMID 35976599›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2023

Health-related quality of life of children born very preterm: a multinational European cohort study.

Sung Wook Kim, Lazaros Andronis, Anna-Veera Seppänen, Adrien M Aubert, Henrique Barros, Elizabeth S Draper, Mariane Sentenac, Jennifer Zeitlin, Stavros Petrou, SHIPS Research Group

Abstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
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  4. More than meets the eye: The hidden burden of temporary feeding tubes on children and their families.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sung Wook KimNuffield Department of Primary Care Health Sciences, University of Oxford, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG, UK. sungwook.kim@phc.ox.ac.uk.ORCID http://orcid.org/0000-0002-1254-5038
Lazaros AndronisWarwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.
Anna-Veera SeppänenUniversité Paris Cité, Inserm, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOPé, 75004, Paris, France.
Adrien M AubertUniversité Paris Cité, Inserm, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOPé, 75004, Paris, France.
Henrique BarrosEPIUnit-Instituto de Saúde Pública da Universidade do Porto, Porto, Portugal.
Elizabeth S DraperDepartment of Health Sciences, University of Leicester, Leicester, UK.
Mariane SentenacUniversité Paris Cité, Inserm, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOPé, 75004, Paris, France.
Jennifer ZeitlinUniversité Paris Cité, Inserm, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOPé, 75004, Paris, France.
Stavros PetrouNuffield Department of Primary Care Health Sciences, University of Oxford, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG, UK.
SHIPS Research Group

Funding

Horizon 2020 633724
6 · The paper itself

Abstract

purposeThis study aims to (1) describe the health-related quality of life (HRQoL) outcomes experienced by children born very preterm (28-31 weeks' gestation) and extremely preterm (< 28 weeks' gestation) at five years of age and (2) explore the mediation effects of bronchopulmonary dysplasia (BPD) and severe non-respiratory neonatal morbidity on those outcomes.

methodsThis investigation was based on data for 3687 children born at < 32 weeks' gestation that contributed to the EPICE and SHIPS studies conducted in 19 regions across 11 European countries. Descriptive statistics and multi-level ordinary linear squares (OLS) regression were used to explore the association between perinatal and sociodemographic characteristics and PedsQL

resultsThe multi-level OLS regression (fully adjusted model) revealed that birth at < 26 weeks' gestation, BPD status and experience of severe non-respiratory morbidity were associated with mean decrements in the total PedsQL

conclusionThe findings suggest that HRQoL is particularly impaired by extremely preterm birth and the concomitant complications of preterm birth such as BPD and severe non-respiratory morbidity.

Indexed as

Bronchopulmonary DysplasiaPremature BirthChildCohort StudiesFemaleHumansInfant, Extremely PrematureInfant, NewbornPregnancyQuality of LifeChildrenMediation analysisPedsQLPreterm birth; health-related quality of life

Identifiers

PMID35976599
PMCPMC9829588

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.