ArticleInsights into imaging2022
Characteristics and outcomes of anterior mediastinal cystic lesions diagnosed on chest MRI: implications for management of cystic lesions.
Article in Insights into imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- [The Clinical Utility of Mediastinal MRI for Evaluating Anterior Mediastinal Masses].Journal of the Korean Society of Radiology · 2026Review
- Rare Posterior Mediastinal Müllerian Cyst Resected by VATS: Case Report and Literature Review.Journal of clinical medicine · 2026Article
- Optimizing Diagnosis and Surgery for Pure Anterior Mediastinal Cysts: Insights from a Single-Centre Study.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Long-term follow-up results of the thymic cysts diagnosed by chest magnetic resonance imaging: single center retrospective study.Journal of thoracic disease · 2025Article
- Inter-reader agreement for diagnosing thymic cysts on chest MRI in two tertiary referral centers.Scientific reports · 2025Article
- Image-guided aspiration of a cystic mediastinal teratoma: A case report and literature review.Radiology case reports · 2024Article
- Computed tomography radiomic feature analysis of thymic epithelial tumors: Differentiation of thymic epithelial tumors from thymic cysts and prediction of histological subtypes.Japanese journal of radiology · 2024Article
- Conventional and radiomic features to predict pathology in the preoperative assessment of anterior mediastinal masses.Lung cancer (Amsterdam, Netherlands) · 2023Article
- MRI-Based Stepwise Approach to Anterior Mediastinal Cystic Lesions for Diagnosis and Further Management.Korean journal of radiology · 2023Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundChest MRI is a useful diagnostic modality for the evaluation of anterior mediastinal lesions but the outcomes of anterior mediastinal cystic lesions diagnosed on chest MRI are unclear.
methodsIn this multicenter retrospective study, patients who underwent contrast-enhanced chest MRI in two tertiary centers to assess anterior mediastinal cystic lesions were included after excluding overt solid tumors and thymic hyperplasia. Anterior mediastinal cystic lesions were classified into two categories: probable (simple) cyst or indeterminate lesion (complex cyst). Size and imaging features of lesions during follow-up were evaluated and clinical outcomes were assessed.
resultsA total of 204 patients (mean age, 59 ± 11 years; M:F = 111:93) were studied; 186 (91.2%) were classified as probable cysts and 18 (8.8%) as indeterminate lesions on MRI. Among patients with probable cysts and more than 2 years of follow-up, lesion size was unchanged in 39.6% (36/91), decreased in 16.5% (15/91), and fluctuated in 8.8% (8/91). All patients who underwent surgery were confirmed cysts. None developed mural nodules or irregular wall thickening, suspicious for malignancy during follow-up. In patients with indeterminate lesions, 16.7% (3/18) had pathologically confirmed thymoma and 44.4% (8/18) had proven cysts. Follow-up numbers and intervals after MRI in patients with probable cysts were variable among physicians and institutions in clinical practice (p < 0.05) but more than half were followed for up to 2 years in two centers.
conclusionDiagnosing anterior mediastinal cysts using MRI is reliable. MRI-based management of anterior mediastinal lesions may reduce the number of unnecessary follow-ups and surgeries.
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