Evidence map›Paper›PMID 35976510›Full record

ReviewInsights into imaging2022

Multi-nuclear magnetic resonance spectroscopy: state of the art and future directions.

Yi Wei, Caiwei Yang, Hanyu Jiang, Qian Li, Feng Che, Shang Wan, Shan Yao, Feifei Gao, Tong Zhang, Jiazheng Wang and 1 more

Abstract readReview
In one paragraph

Review in Insights into imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Translational andrology and urology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Hyperpolarized [1-Brain communications · 2025
    Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Odd-Leg Birdcages for Geometric Decoupling in Multinuclear Imaging and Spectroscopy.Concepts in magnetic resonance. Part B, Magnetic resonance engineering · 2023
    Article
  15. Multinuclear MRI in Drug Discovery.Molecules (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yi Wei *Department of Radiology, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Chengdu, 610041, People's Republic of China.
Caiwei Yang *Department of Radiology, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Chengdu, 610041, People's Republic of China.
Hanyu JiangDepartment of Radiology, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Chengdu, 610041, People's Republic of China.
Qian LiDepartment of Radiology, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Chengdu, 610041, People's Republic of China.
Feng CheDepartment of Radiology, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Chengdu, 610041, People's Republic of China.
Shang WanDepartment of Radiology, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Chengdu, 610041, People's Republic of China.
Shan YaoDepartment of Radiology, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Chengdu, 610041, People's Republic of China.
Feifei GaoDepartment of Radiology, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Chengdu, 610041, People's Republic of China.
Tong ZhangDepartment of Radiology, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Chengdu, 610041, People's Republic of China.
Jiazheng WangClinical & Technical Support, Philips Healthcare, Beijing, China.
Bin SongDepartment of Radiology, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Chengdu, 610041, People's Republic of China. songlab_radiology@163.com.ORCID http://orcid.org/0000-0002-7269-2101

Funding

Doctor Research Project, West China Hospital, Sichuan University 2020HXBH130Postdoctoral Research Foundation of China 2021M692289Sichuan Province Science and Technology Support Program 2021YFS0021Sichuan Province Science and Technology Support Program 2021YFS0144
6 · The paper itself

Abstract

With the development of heteronuclear fluorine, sodium, phosphorus, and other probes and imaging technologies as well as the optimization of magnetic resonance imaging (MRI) equipment and sequences, multi-nuclear magnetic resonance (multi-NMR) has enabled localize molecular activities in vivo that are central to a variety of diseases, including cardiovascular disease, neurodegenerative pathologies, metabolic diseases, kidney, and tumor, to shift from the traditional morphological imaging to the molecular imaging, precision diagnosis, and treatment mode. However, due to the low natural abundance and low gyromagnetic ratios, the clinical application of multi-NMR has been hampered. Several techniques have been developed to amplify the NMR sensitivity such as the dynamic nuclear polarization, spin-exchange optical pumping, and brute-force polarization. Meanwhile, a wide range of nuclei can be hyperpolarized, such as

Indexed as

Clinical applicationHyperpolarizationMagnetic resonance spectroscopic imagingMulti-nuclear magnetic resonance

Identifiers

PMID35976510
PMCPMC9382599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.