Trial reportClinical oral investigations2022
Bleaching efficacy and quality of life of different bleaching techniques - randomized controlled trial.
Trial report in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Bleaching Regimen With Different Activation Modes on Color Stability, Surface Roughness, Tooth Sensitivity and Patient Satisfaction
Clinical Evaluation of Color Changes (CIELAB),Whiteness Index (WID), and Oral Health-Related Quality of Life (OHIP-14) Following At-home Dental Bleaching: A Prospective Clinical Study
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Comparative efficacy of external dental bleaching gels: a systematic review of whitening performance and longevity.Clinical oral investigations · 2025Pooled it
- Efficacy of topical drug application to manage in-office bleaching sensitivity: a systematic review and meta-analysis of randomized clinical trials.Clinical oral investigations · 2024Pooled it
- Evaluating the Efficiency and Tooth Sensitivity of a Novel Whitening Strip: A Randomized, Double-Blind Controlled Trial.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026Trial
- Clinical evaluation of in-office bleaching with low, medium, and high concentrate hydrogen peroxide: a 6-month a double-blinded randomized controlled trial.Clinical oral investigations · 2025Trial
- Objective Image-Based Assessment of Tooth Translucency Changes Following Different Bleaching Protocols: A Retrospective Cohort Study.Biomimetics (Basel, Switzerland) · 2026Article
- Comparative Evaluation of Different Teeth Whitening Agents on Extrinsic Stains: An In-Vitro Interventional Study.Journal of clinical and experimental dentistry · 2026Review
- The Effect of Home Bleaching Gel with Chitosan on Tooth Color and Mineral Alteration.Gels (Basel, Switzerland) · 2025Article
- The Efficacy of 3 Bleaching Methods on Stained Polymer-Based CAD/CAM Materials.International dental journal · 2025Article
- Whitening: is Omnichroma universal composite unchanging? Spectrophotometric evaluation.Journal of clinical and experimental dentistry · 2024Article
- New Insights Regarding the Use of Relevant Synthetic Compounds in Dentistry.Molecules (Basel, Switzerland) · 2024Review
- Effect of Various Vital Bleaching Systems on Clinical Outcomes and Patient Satisfaction.Cureus · 2024Article
- Evaluating the efficiency of two different over-the-counter tooth whitening systems: a randomised controlled clinical trial.BDJ open · 2024Article
- Assessment of Color Change, Esthetic Perception, Treatment Satisfaction, and Side Effects Following the Use of Over-the-Counter Whitening Products.Acta stomatologica Croatica · 2023Article
- Hydrogen Peroxide Diffusion through Dental Tissues-In Vitro Study.Materials (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate bleaching efficacy and oral health-related quality of life (ORHQoL) of three bleaching systems with similar hydrogen peroxide (HP) concentration for up to 6 months post-treatment. MATERIALS AND
methodsA randomized controlled trial was designed with three parallel groups: group A - in-office 6% HP paint-on varnish; group B - at-home 6% HP with adaptable tray; group C - at-home 16% carbamide peroxide with custom tray. At three different stages (baseline, after bleaching, and 6-month follow-up), ORHQoL was evaluated by the OHIP-14 questionnaire and tooth color of the upper canines and central incisors were measured by two shade guides and a spectrophotometer (measuring CIE L*a*b* with respective color/whiteness differences - ΔE
resultsAll groups presented significant color differences (P < 0.05) between all stages, with ΔE
conclusionsAll techniques presented bleaching efficacy, color stability, and improvements in ORHQoL up to 6 months post-treatment. CLINICAL SIGNIFICANCE: Clinicians may consider both at-home and in-office bleaching techniques with 6% HP to attain long-lasting satisfactory clinical results while producing positive changes in ORHQoL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.