SynthesisClinical research in cardiology : official journal of the German Cardiac Society2023
Pulmonary embolism response team (PERT) implementation and its clinical value across countries: a scoping review and meta-analysis.
Synthesis in Clinical research in cardiology : official journal of the German Cardiac Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 81 citations in OpenAlex.
- Endovascular reperfusion strategies for pregnancy-related pulmonary embolism: a systematic review.Journal of thrombosis and thrombolysis · 2026Pooled it
- Assessing the impact of intermediate care interventions on healthcare and patient-related outcomes: a systematic overview of systematic reviews.BMC health services research · 2025Pooled it
- Current Insights for Catheter-Directed Therapies in Acute Pulmonary Embolism: Systematic Review and Our Single-Center Experience.Anatolian journal of cardiology · 2023Pooled it
- Integrating pulmonary embolism response teams: perspectives and outcomes from a European and German survey analysis.Thrombosis journal · 2026Article
- How patient profile and hospital setting drive pulmonary embolism treatment modality.Journal of vascular surgery. Venous and lymphatic disorders · 2026Article
- Outcomes of catheter-directed mechanical thrombectomy in patients with cancer-associated pulmonary embolism: a multicenter, prospective registry.Research and practice in thrombosis and haemostasis · 2026Observational
- A simple score to identify the sickest normotensive patients with acute pulmonary embolism.ERJ open research · 2026Article
- Imaging-Driven Risk Stratification and Endovascular Decision Pathways in Acute Pulmonary Embolism.Diagnostics (Basel, Switzerland) · 2026Review
- NEWS-Guided Management of Pulmonary Embolism in Pregnancy With Percutaneous Thrombectomy.JACC. Case reports · 2026Article
- Safety and efficacy of thrombolysis with the EkoSonic Endovascular System for intermediate-high risk pulmonary embolism during on- and off-hours: a multicenter study.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- A study on the relationship between mMRC dyspnea scale and both risk stratification and poor prognosis in patients with acute pulmonary embolism.Frontiers in cardiovascular medicine · 2026Article
- Contemporary reperfusion therapies in patients with intermediate- and high-risk pulmonary embolism.Thrombosis research · 2025Article
- Process and outcome evaluation of a regional pulmonary embolism response team.Thrombosis journal · 2025Article
- Socioeconomic Burden of Pulmonary Embolism in Europe: Shifting Priorities and Challenges for Novel Reperfusion Strategies.Thrombosis and haemostasis · 2025Review
- Effects of Implementing a Standardized Risk Stratification and Triage Workflow for an Established Pulmonary Embolism Response Team.Annals of the American Thoracic Society · 2025Article
- L-Shaped Association of 24-Hour Urine Output with 3-Month and 1-Year All-Cause Mortality in Patients with Acute Pulmonary Embolism: A Retrospective Cohort Study.Journal of atherosclerosis and thrombosis · 2025Article
- Physician Survey on the Management of Pulmonary Embolism in Pregnancy: Need for Guidance and Training.EJHaem · 2025Article
- Mechanical circulatory support in acute pulmonary embolism.European heart journal supplements : journal of the European Society of Cardiology · 2025Article
- Characteristics and Outcomes of Pulmonary Embolism Patients Transferred After Activation of Pulmonary Embolism Response Team and Admitted from Local Emergency Department.Journal of clinical medicine · 2025Article
- Achieving equitable care in pulmonary embolism: exploring the potential of pulmonary embolism response teams.Blood advances · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOver the last years, multidisciplinary pulmonary embolism response teams (PERTs) have emerged to encounter the increasing variety and complexity in the management of acute pulmonary embolism (PE). We aimed to systematically investigate the composition and added clinical value of PERTs.
methodsWe searched PubMed, CENTRAL and Web of Science until January 2022 for articles designed to describe the structure and function of PERTs. We performed a random-effects meta-analysis of controlled studies (PERT vs. pre-PERT era) to investigate the impact of PERTs on clinical outcomes and advanced therapies use.
resultsWe included 22 original studies and four surveys. Overall, 31.5% of patients with PE were evaluated by PERT referred mostly by emergency departments (59.4%). In 11 single-arm studies (1532 intermediate-risk and high-risk patients evaluated by PERT) mortality rate was 10%, bleeding rate 9% and length of stay 7.3 days [95% confidence interval (CI) 5.7-8.9]. In nine controlled studies there was no difference in mortality [risk ratio (RR) 0.89, 95% CI 0.67-1.19] by comparing pre-PERT with PERT era. When analysing patients with intermediate or high-risk class only, the effect estimate for mortality tended to be lower for patients treated in the PERT era compared to those treated in the pre-PERT era (RR 0.71, 95% CI 0.45-1.12). The use of advanced therapies was higher (RR 2.67, 95% CI 1.29-5.50) and the in-hospital stay shorter (mean difference - 1.6 days) in PERT era compared to pre-PERT era.
conclusionsPERT implementation led to greater use of advanced therapies and shorter in-hospital stay. Our meta-analysis did not show a survival benefit in patients with PE since PERT implementation. Large prospective studies are needed to further explore the impact of PERTs on clinical outcomes. REGISTRATION: Open Science Framework 10.17605/OSF.IO/SBFK9.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.