Evidence map›Paper›PMID 35976320›Full record

ReviewArquivos de neuro-psiquiatria2022

Magnetic resonance and dopamine transporter imaging for the diagnosis of Parkinson´s disease: a narrative review.

Rafael Tomio Vicentini Otani, Joyce Yuri Silvestre Yamamoto, Douglas Mendes Nunes, Mônica Santoro Haddad, Jacy Bezerra Parmera

Open access · goldAbstract readReview
In one paragraph

Review in Arquivos de neuro-psiquiatria, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rafael Tomio Vicentini OtaniUniversidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Neurologia, São Paulo SP, Brazil.ORCID 0000-0003-2954-5592
Joyce Yuri Silvestre YamamotoUniversidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Neurologia, São Paulo SP, Brazil.ORCID 0000-0001-7074-2112
Douglas Mendes NunesUniversidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departmento de Radiologia e Oncologia, Instituto de Radiologia, São Paulo SP, Brazil.ORCID 0000-0002-2908-9569
Mônica Santoro HaddadUniversidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Neurologia, São Paulo SP, Brazil.ORCID 0000-0002-5298-1686
Jacy Bezerra ParmeraUniversidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Neurologia, São Paulo SP, Brazil.ORCID 0000-0002-3565-5328
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundthe diagnosis of Parkinson's disease (PD) can be challenging, especially in the early stages, albeit its updated and validated clinical criteria. Recent developments on neuroimaging in PD, altogether with its consolidated role of excluding secondary and other neurodegenerative causes of parkinsonism, provide more confidence in the diagnosis across the different stages of the disease. This review highlights current knowledge and major recent advances in magnetic resonance and dopamine transporter imaging in aiding PD diagnosis.

objectiveThis study aims to review current knowledge about the role of magnetic resonance imaging and neuroimaging of the dopamine transporter in diagnosing Parkinson's disease.

methodsWe performed a non-systematic literature review through the PubMed database, using the keywords "Parkinson", "magnetic resonance imaging", "diffusion tensor", "diffusion-weighted", "neuromelanin", "nigrosome-1", "single-photon emission computed tomography", "dopamine transporter imaging". The search was restricted to articles written in English, published between January 2010 and February 2022.

resultsThe diagnosis of Parkinson's disease remains a clinical diagnosis. However, new neuroimaging biomarkers hold promise for increased diagnostic accuracy, especially in earlier stages of the disease.

conclusionFuture validation of new imaging biomarkers bring the expectation of an increased neuroimaging role in the diagnosis of PD in the following years.

Indexed as

Dopamine Plasma Membrane Transport ProteinsParkinson DiseaseBiomarkersHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyNeuroimagingBiomarkersDopamine Plasma Membrane Transport Proteins

Identifiers

PMID35976320
PMCPMC9491424
OpenAlexW4290975828

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.