ArticleEnvironmental health perspectives2022
Unconventional Oil and Gas Development Exposure and Risk of Childhood Acute Lymphoblastic Leukemia: A Case-Control Study in Pennsylvania, 2009-2017.
Article in Environmental health perspectives, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- The public health impacts of mining in Australia.The Medical journal of Australia · 2025Pooled it
- GAS flaring and cancer in the Amazon of Ecuador: an ecological study.Global health action · 2026Article
- Microplastics at the Intersection of Toxicology, Child Health, and Human Rights.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026Article
- School-based exposures to oil and gas development for public school children in the United States.Journal of exposure science & environmental epidemiology · 2026Article
- High Childhood Leukemia Mortality Rates in Mexico Associated to Water Contamination in Areas of Oil and Gas Extraction.GeoHealth · 2026Article
- Maternal residential proximity to oil and gas development in California and the risk of childhood cancer.International journal of hygiene and environmental health · 2026Article
- Modelling spatial heterogeneity in exposure buffers and risk: a hierarchical Bayesian approach.Journal of the Royal Statistical Society. Series C, Applied statistics · 2026Article
- Residential proximity to active and abandoned oil and gas development and risk of childhood Ewing sarcoma in California.Environmental health : a global access science source · 2026Article
- The Mutational Epidemiology of Childhood Cancer.Clinical chemistry · 2025Review
- Using Geoscientific Analysis and Community Engagement to Analyze Exposures to Potential Groundwater Contamination Related to Hydrocarbon Extraction in Southwestern Pennsylvania.Research report (Health Effects Institute) · 2025Article
- High populations near fossil fuel energy infrastructure across the supply chain and implications for an equitable energy transition.Environmental research letters : ERL [Web site] · 2025Article
- Original research article: popexposure: An open-source Python package to find the number of people residing near environmental hazards quickly and efficiently.medRxiv : the preprint server for health sciences · 2025Article
- Exposures from Oil and Gas Development and Childhood Leukemia Risk in Colorado: A Population-Based Case-Control Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Article
- Cumulative Human Health Risk Assessment of Regional Ozone and Volatile Organic Compounds from Unconventional Oil and Gas Sites in Colorado's Front Range.Environmental health perspectives · 2025Article
- A Narrative Review of Spatial-Temporal Data Sources for Estimating Population-Level Exposures to Oil and Gas Development in the United States.Current environmental health reports · 2025Review
- Cumulative Exposure to Unconventional Natural Gas Development and the Risk of Childhood Cancer: A Registry-Based Case-Control Study.International journal of environmental research and public health · 2025Article
- Predictors of early life residential mobility in urban and rural Pennsylvania children with acute lymphoblastic leukemia and implications for environmental exposure assessment.Journal of exposure science & environmental epidemiology · 2024Article
- Wastewaters Coproduced with Shale Gas Drive Slight Regional Salinization of Groundwater.Environmental science & technology · 2024Article
- The human health effects of unconventional oil and gas development (UOGD): A scoping review of epidemiologic studies.Canadian journal of public health = Revue canadienne de sante publique · 2024Article
- Air Quality and Health Impacts of Onshore Oil and Gas Flaring and Venting Activities Estimated Using Refined Satellite-Based Emissions.GeoHealth · 2024Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundUnconventional oil and gas development (UOGD) releases chemicals that have been linked to cancer and childhood leukemia. Studies of UOGD exposure and childhood leukemia are extremely limited.
objectiveThe objective of this study was to evaluate potential associations between residential proximity to UOGD and risk of acute lymphoblastic leukemia (ALL), the most common form of childhood leukemia, in a large regional sample using UOGD-specific metrics, including a novel metric to represent the water pathway.
methodsWe conducted a registry-based case-control study of 405 children ages 2-7 y diagnosed with ALL in Pennsylvania between 2009-2017, and 2,080 controls matched on birth year. We used logistic regression to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for the association between residential proximity to UOGD (including a new water pathway-specific proximity metric) and ALL in two exposure windows: a primary window (3 months preconception to 1 y prior to diagnosis/reference date) and a perinatal window (preconception to birth).
resultsChildren with at least one UOG well within DISCUSSION: Our study including a novel UOGD metric found UOGD to be a risk factor for childhood ALL. This work adds to mounting evidence of UOGD's impacts on children's health, providing additional support for limiting UOGD near residences. https://doi.org/10.1289/EHP11092.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.