Evidence map›Paper›PMID 35975888›Full record

ArticleAJR. American journal of roentgenology2023

Effect of GBCA Use on Detection and Diagnostic Performance of the Central Vein Sign: Evaluation Using a 3-T FLAIR* Sequence in Patients With Suspected Multiple Sclerosis.

Lynn Daboul, Carly M O'Donnell, Quy Cao, Moein Amin, Paulo Rodrigues, John Derbyshire, Christina Azevedo, Amit Bar-Or, Eduardo Caverzasi, Peter Calabresi and 18 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in AJR. American journal of roentgenology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Incorporation of the central vein sign into the McDonald criteria.Multiple sclerosis and related disorders · 2025
    Article
  4. Review
  5. Article
  6. Choroid plexus volume differentiates MS from its mimics.Multiple sclerosis (Houndmills, Basingstoke, England) · 2024
    Article
  7. Multicenter validation of automated detection of paramagnetic rim lesions on brain MRI in multiple sclerosis.Journal of neuroimaging : official journal of the American Society of Neuroimaging
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

28 authors at 14 institutions in 2 countries.

Lynn DaboulDepartment of Neurology, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115.
Carly M O'DonnellDepartment of Biostatistics, Epidemiology, and Informatics, Penn Statistics in Imaging and Visualization Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Quy CaoDepartment of Biostatistics, Epidemiology, and Informatics, Penn Statistics in Imaging and Visualization Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Moein AminNeurological Institute, Cleveland Clinic, Cleveland, OH.
Paulo RodriguesQMENTA, Inc., Boston, MA.
John DerbyshireFunctional MRI Facility, NIMH, NIH, Bethesda, MD.
Christina AzevedoDepartment of Neurology, University of Southern California, Los Angeles, CA.
Amit Bar-OrDepartment of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Eduardo CaverzasiDepartment of Neurology, University of California at San Francisco, San Francisco, CA.
Peter CalabresiDepartment of Neurology, Johns Hopkins University, Baltimore, MD.
Bruce A C CreeDepartment of Neurology, University of California at San Francisco, San Francisco, CA.
Leorah FreemanDepartment of Neurology, Dell Medical School, The University of Texas at Austin, Austin, TX.
Roland G HenryDepartment of Neurology, University of California at San Francisco, San Francisco, CA.
Erin E LongbrakeDepartment of Neurology, Yale University, New Haven, CT.
Kunio NakamuraDepartment of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH.
Jiwon OhDivision of Neurology, St. Michael's Hospital, University of Toronto, ON, Canada.
Nico PapinuttoDepartment of Neurology, University of California at San Francisco, San Francisco, CA.
Daniel PelletierDepartment of Neurology, University of Southern California, Los Angeles, CA.
Rohini D SamudralwarDepartment of Neurology, The University of Texas Health Science Center at Houston, Houston, TX.
Suradech SuthiphosuwanDepartment of Medical Imaging, St. Michael's Hospital, University of Toronto, ON, Canada.
Matthew K SchindlerDepartment of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Elias S SotirchosDepartment of Neurology, Johns Hopkins University, Baltimore, MD.
Nancy L SicotteDepartment of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA.
Andrew J SolomonDepartment of Neurological Sciences, Larner College of Medicine, The University of Vermont, Burlington, VT.
Russell T ShinoharaDepartment of Biostatistics, Epidemiology, and Informatics, Penn Statistics in Imaging and Visualization Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Daniel S ReichTranslational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD.
Daniel OntanedaMellen Center for Multiple Sclerosis, Cleveland Clinic, Cleveland, OH.
Pascal SatiTranslational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD.
University of California, San Francisco · USCedars-Sinai Medical Center · USCleveland Clinic · USCleveland Clinic Lerner College of Medicine · USJohns Hopkins University · USUniversity of Pennsylvania · USUniversity of Southern California · USNational Institutes of Health · USSt. Michael's Hospital · CAThe University of Texas at Austin · USThe University of Texas Health Science Center at Houston · USUniversity of Toronto · CAUniversity of Vermont · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Multimodal MRI in Multiple SclerosisZIANS003119 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI REICH, DANIEL · 2010 to 2025
$53.4M
Harmonization of Multi-Site Neuroimaging Data from Complex Study DesignsR01MH123550 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI SHINOHARA, RUSSELL TAKESHI · 2020 to 2025
$4.0M
Advanced Statistical Analytics of MRI in MSR01NS112274 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI SHINOHARA, RUSSELL TAKESHI · 2020 to 2024
$2.8M
Interactions between Gut Microbiome and B-Cell Depletion in Multiple SclerosisK23NS107624 · NINDS · YALE UNIVERSITY · PI LONGBRAKE, ERIN · 2019 to 2023
$980k
NCATS NIH HHS UL1 TR001863NIMH NIH HHS R01 MH123550NINDS NIH HHS K23 NS107624NINDS NIH HHS R01 NS112274
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Multiple SclerosisVascular DiseasesAdultBrainContrast MediaFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPilot ProjectsProspective StudiesContrast Mediacentral vein signFLAIR*gadoliniummultiple sclerosis

Identifiers

PMID35975888
PMCPMC10016223
OpenAlexW4292099787

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.