Evidence map›Paper›PMID 35975793›Full record

ArticleCardiology journal2024

The prognostic impact of therapeutic hypothermia after a sudden cardiac arrest in the course of myocardial infarction.

Agata Sobczyk, Witold Streb, Andrzej Świątkowski, Jacek Kowalczyk, Zbigniew Kalarus, Beata Średniawa

Open access · goldAbstract read
In one paragraph

Article in Cardiology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Agata SobczykDoctoral School, Medical University of Silesia, Katowice, Poland. agatka_kapalka@poczta.fm.ORCID 0000-0001-9677-493X
Witold Streb1st Department of Cardiology and Angiology, Silesian Center for Heart Diseases, Zabrze, Poland.ORCID 0000-0003-4856-8511
Andrzej Świątkowski1st Department of Cardiology and Angiology, Silesian Center for Heart Diseases, Zabrze, Poland.
Jacek Kowalczyk1st Department of Cardiology and Angiology, Silesian Center for Heart Diseases, Zabrze, Poland.ORCID 0000-0003-3836-9041
Zbigniew Kalarus1st Department of Cardiology and Angiology, Silesian Center for Heart Diseases, Zabrze, Poland.ORCID 0000-0003-3921-7234
Beata Średniawa1st Department of Cardiology and Angiology, Silesian Center for Heart Diseases, Zabrze, Poland.ORCID 0000-0003-1591-3972
Silesian Center for Heart Disease · PLMedical University of Silesia · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMild therapeutic hypothermia (MTH) is one of the treatment methods recommended in post-sudden cardiac arrest (SCA) patients who remain unconscious after cardiopulmonary resuscitation. The present study aimed at assessing the prognostic impact of intravascular MTH on invasively treated patients with an acute myocardial infarction complicated by SCA.

methodsThe presented data were collected via a single-center retrospective analysis of the hospitalization and follow-up of 54 patients with post-myocardial infarction complicated by SCA. The patients were treated in the years 2014-2020 and the average follow-up period was 1141 ± 163 days. The population was divided into two groups: 28 patients treated with MTH (a therapeutic hypothermia [TH] group) and 26 patients treated without MTH (a non-TH group).

resultsThe results indicate a trend toward improved in-hospital prognosis in the TH group, but the differences did not reach statistical significance: TH 25.0% vs. non-TH 34.5%, p = 0.554. An additional analysis of younger patients (under 60 years of age) revealed no significant differences between the TH and non-TH subgroups concerning in-hospital survival (in-hospital mortality rate: TH 6.7% vs. non-TH 30.0%, p = 0.267). Still, TH patients aged < 60 achieved a significantly better rate of follow-up survival (p = 0.041). The older (≥ 60) patient group showed no in-hospital mortality rate differences (TH 46.2% vs. non-TH 37.5%, p = 0.638). However, in-hospital bleeding frequency was significantly higher in patients aged ≥ 60 from the hypothermia group (TH 50.0% vs. non-TH 6.7%, p = 0.011).

conclusionsIntravascular MTH may improve the follow-up prognosis in patients aged < 60 with SCA in the early phase of myocardial infarction.

Indexed as

Hospital MortalityHypothermia, InducedMyocardial InfarctionAgedCardiopulmonary ResuscitationDeath, Sudden, CardiacFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsSurvival RateTime Factorscardiac arrestmyocardial infarctiontarget temperature managementtherapeutic hypothermia

Identifiers

PMID35975793
PMCPMC11544403
OpenAlexW4292289388

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.