Evidence map›Paper›PMID 35975663›Full record

Trial reportStroke2022

Home-Based Transcranial Direct Current Stimulation to Enhance Cognition in Stroke: Randomized Controlled Trial.

Myoung-Hwan Ko, Ju-Yul Yoon, Yun-Ju Jo, Mi-Nam Son, Da-Sol Kim, Gi-Wook Kim, Yu Hui Won, Sung-Hee Park, Jeong-Hwan Seo, Yun-Hee Kim

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Stroke, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 7 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 7 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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  4. Effects of home-based neurostimulation on outcomes after stroke: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
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  16. The enigma of vascular dementia: current state and emerging perspectives.Journal of neural transmission (Vienna, Austria : 1996) · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Myoung-Hwan Ko *Department of Physical Medicine and Rehabilitation, Jeonbuk National University Medical School, Jeonju, Republic of Korea (M.-H.K., J.-Y.Y., D.-S.K., G.-W.K., Y.H.W., S.-H.P., J.-H.S.).ORCID 0000-0002-0566-3677
Ju-Yul Yoon *Department of Physical Medicine and Rehabilitation, Jeonbuk National University Medical School, Jeonju, Republic of Korea (M.-H.K., J.-Y.Y., D.-S.K., G.-W.K., Y.H.W., S.-H.P., J.-H.S.).ORCID 0000-0002-2379-6158
Yun-Ju JoTranslational Research & Clinical Trials Center for Medical Devices, Jeonbuk National University Hospital, Jeonju, Republic of Korea (M.-H.K., Y.-J.J., G.-W.K.).ORCID 0000-0002-1307-8371
Mi-Nam SonDepartment of Physical and Rehabilitation Medicine, Center for Prevention and Rehabilitation, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea (M.-N.S., Y.-H.K.).ORCID 0000-0002-4442-5989
Da-Sol KimDepartment of Physical Medicine and Rehabilitation, Jeonbuk National University Medical School, Jeonju, Republic of Korea (M.-H.K., J.-Y.Y., D.-S.K., G.-W.K., Y.H.W., S.-H.P., J.-H.S.).
Gi-Wook KimDepartment of Physical Medicine and Rehabilitation, Jeonbuk National University Medical School, Jeonju, Republic of Korea (M.-H.K., J.-Y.Y., D.-S.K., G.-W.K., Y.H.W., S.-H.P., J.-H.S.).
Yu Hui WonDepartment of Physical Medicine and Rehabilitation, Jeonbuk National University Medical School, Jeonju, Republic of Korea (M.-H.K., J.-Y.Y., D.-S.K., G.-W.K., Y.H.W., S.-H.P., J.-H.S.).
Sung-Hee ParkDepartment of Physical Medicine and Rehabilitation, Jeonbuk National University Medical School, Jeonju, Republic of Korea (M.-H.K., J.-Y.Y., D.-S.K., G.-W.K., Y.H.W., S.-H.P., J.-H.S.).
Jeong-Hwan SeoDepartment of Physical Medicine and Rehabilitation, Jeonbuk National University Medical School, Jeonju, Republic of Korea (M.-H.K., J.-Y.Y., D.-S.K., G.-W.K., Y.H.W., S.-H.P., J.-H.S.).ORCID 0000-0002-6915-6674
Yun-Hee KimDepartment of Physical and Rehabilitation Medicine, Center for Prevention and Rehabilitation, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea (M.-N.S., Y.-H.K.).ORCID 0000-0001-6101-8851
Jeonbuk National University Hospital · KRSamsung Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTranscranial direct current stimulation (tDCS) is a promising tool for improving poststroke cognitive function. Home-based rehabilitation is increasingly required for patients with stroke, and additional benefits are expected if supplemented with remotely supervised tDCS (RS-tDCS). We evaluated the cognitive improvement effect and feasibility of RS-tDCS in patients with chronic stroke.

methodsTwenty-six patients with chronic stroke and cognitive impairment (Korean version of the Montreal Cognitive Assessment [K-MoCA] score <26) were randomized into real and sham RS-tDCS groups and underwent concurrent computerized cognitive training and RS-tDCS. Patients and caregivers underwent training to ensure correct tDCS self-application, were monitored, and treated 5 d/wk for 4 weeks. We investigated several cognition tests including K-MoCA, Korean version of the Dementia Rating Scale-2, Korean-Boston Naming Test, Trail Making Test, Go/No Go, and Controlled Oral Word Association Test at the end of the training sessions and one month later. Repeated-measures ANOVA was used for comparison between the groups and within each group. The adherence rate of the appropriate RS-tDCS session was also investigated.

resultsIn within-group comparison, unlike the sham group, the real group showed significant improvement in K-MoCA (

conclusionsRS-tDCS is a safe and feasible rehabilitation modality for poststroke cognitive dysfunction. Specifically, RS-tDCS is effective in patients with moderate cognitive decline. Additionally, these data demonstrate the potential to enhance home-based cognitive training, although significant differences were not consistently found in between-group comparisons; therefore, further larger studies are needed. REGISTRATION: URL: https://cris.nih.go.kr; Unique identifier: KCT0003427.

Indexed as

Cognition DisordersStrokeStroke RehabilitationTranscranial Direct Current StimulationCognitionDouble-Blind MethodHumanscognitive dysfunctionstroketelerehabilitationtranscranial direct current stimulation

Identifiers

PMID35975663
OpenAlexW4292319854

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.