Evidence map›Paper›PMID 35975427›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022

Implantable Electroceutical Approach Improves Myelination by Restoring Membrane Integrity in a Mouse Model of Peripheral Demyelinating Neuropathy.

Aseer Intisar, Hyun Young Shin, Woon-Hae Kim, Hyun Gyu Kang, Min Young Kim, Yu Seon Kim, Youngjun Cho, Yun Jeoung Mo, Heejin Lim, Sanghoon Lee and 3 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Silver electroceutical technology to treat sarcopenia.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Aseer IntisarDepartment of New Biology, DGIST, Daegu, 42988, Republic of Korea.
Hyun Young ShinCTCELLS Corp., Daegu, 42988, Republic of Korea.
Woon-Hae KimCTCELLS Corp., Daegu, 42988, Republic of Korea.
Hyun Gyu KangDepartment of New Biology, DGIST, Daegu, 42988, Republic of Korea.
Min Young KimDepartment of New Biology, DGIST, Daegu, 42988, Republic of Korea.
Yu Seon KimWell Aging Research Center, DGIST, Daegu, 42988, Republic of Korea.
Youngjun ChoDepartment of Robotics and Mechatronics Engineering, DGIST, Daegu, 42988, Republic of Korea.
Yun Jeoung MoWell Aging Research Center, DGIST, Daegu, 42988, Republic of Korea.
Heejin LimDepartment of New Biology, DGIST, Daegu, 42988, Republic of Korea.
Sanghoon LeeDepartment of Robotics and Mechatronics Engineering, DGIST, Daegu, 42988, Republic of Korea.
Q Richard LuDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.
Yun-Il LeeWell Aging Research Center, DGIST, Daegu, 42988, Republic of Korea.
Minseok S KimDepartment of New Biology, DGIST, Daegu, 42988, Republic of Korea.ORCID 0000-0002-4268-6886
Daegu Gyeongbuk Institute of Science and Technology · KRNovaCell Technology (South Korea) · KRCincinnati Children's Hospital Medical Center · US

Funding

Samsung Research Funding & Incubation Center for Future Technology SRFC-IT1701-10
6 · The paper itself

Abstract

Although many efforts are undertaken to treat peripheral demyelinating neuropathies based on biochemical interventions, unfortunately, there is no approved treatment yet. Furthermore, previous studies have not shown improvement of the myelin membrane at the biomolecular level. Here, an electroceutical treatment is introduced as a biophysical intervention to treat Charcot-Marie-Tooth (CMT) disease-the most prevalent peripheral demyelinating neuropathy worldwide-using a mouse model. The specific electrical stimulation (ES) condition (50 mV mm

Indexed as

Charcot-Marie-Tooth DiseaseDemyelinating DiseasesAnimalsDisease Models, AnimalMyelin SheathProteinsProteinsCharcot-Marie-Tooth diseasecholesterolelectroceuticalsmyelinationmyelin membrane integrityperipheral demyelinating neuropathiesPMP22

Identifiers

PMID35975427
PMCPMC9661852
OpenAlexW4292080583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.