Evidence map›Paper›PMID 35975164›Full record

ArticleEnvironmental epidemiology (Philadelphia, Pa.)2022

Exposure to natural vegetation in relation to mammographic density in a Massachusetts-based clinical cohort.

Lyndsey K Blair, Erica T Warner, Peter James, Jaime E Hart, Trang VoPham, Mollie E Barnard, Johnnie D Newton, Divya J Murthy, Francine Laden, Rulla M Tamimi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Environmental epidemiology (Philadelphia, Pa.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Lyndsey K BlairDepartment of Epidemiology and Population Health, University of Louisville, School of Public Health and Information Sciences, Louisville, Kentucky.
Erica T WarnerDepartment of Medicine, Mongan Institute, Clinical Translational Epidemiology Unit, Massachusetts General Hospital, Boston, Massachusetts.
Peter JamesDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts.
Jaime E HartDepartment of Environmental Health, Harvard TH Chan School of Public Health, Boston, Massachusetts.
Trang VoPhamEpidemiology Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Mollie E BarnardDepartment of Population Health Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.
Johnnie D NewtonDepartment of Epidemiology and Population Health, University of Louisville, School of Public Health and Information Sciences, Louisville, Kentucky.
Divya J MurthyChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Francine LadenDepartment of Environmental Health, Harvard TH Chan School of Public Health, Boston, Massachusetts.
Rulla M TamimiDepartment of Population Health Sciences, Weill Cornell Medical, New York, New York.
Natalie C DuPreDepartment of Epidemiology and Population Health, University of Louisville, School of Public Health and Information Sciences, Louisville, Kentucky.
Brigham and Women's Hospital · USUniversity of Louisville · USCornell University · USFred Hutch Cancer Center · USHarvard Pilgrim Health Care · USHuntsman Cancer Institute · USMassachusetts General Hospital · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
Training Program in Cancer EpidemiologyT32CA009001 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI A. Heather Eliassen, Meir Stampfer · 1985 to 2026
$17.3M
University of Louisville Center for Integrative Environmental Health SciencesP30ES030283 · NIEHS · UNIVERSITY OF LOUISVILLE · PI Amanda Jo LeBlanc · 2020 to 2026
$10.0M
UOFL ENVIRONMENTAL HEALTH SCIENCES TRAINING PROGRAMT32ES011564 · NIEHS · UNIVERSITY OF LOUISVILLE · PI David W Hein, John Pierce Wise · 2004 to 2026
$7.1M
Built Environment Assessment through Computer visiON (BEACON): Applying Deep Learning to Street-Level and Satellite Images to Estimate Built Environment Effects on Cardiovascular HealthR01HL150119 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JAMES, PETER · 2020 to 2024
$3.9M
Race/Ethnicity and Mammographic Density: Genetic and Lifestyle FactorsK01CA188075 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI WARNER, ERICA T · 2014 to 2017
$518k
Inflammation and gynecologic cancer: the role of prostaglandins in ovarian cancerK00CA212222 · NCI · UNIVERSITY OF UTAH · PI BARNARD, MOLLIE ELYSE · 2018 to 2021
$415k
NCI NIH HHS K00 CA212222NCI NIH HHS K01 CA188075NCI NIH HHS T32 CA009001NHLBI NIH HHS R01 HL150119NIEHS NIH HHS P30 ES000002NIEHS NIH HHS P30 ES030283NIEHS NIH HHS T32 ES011564
6 · The paper itself

Abstract

Inverse associations between natural vegetation exposure (i.e., greenness) and breast cancer risk have been reported; however, it remains unknown whether greenness affects breast tissue development or operates through other mechanisms (e.g., body mass index [BMI] or physical activity). We examined the association between greenness and mammographic density-a strong breast cancer risk factor-to determine whether greenness influences breast tissue composition independent of lifestyle factors. Methods: Women (n = 2,318) without a history of breast cancer underwent mammographic screening at Brigham and Women's Hospital in Boston, Massachusetts, from 2006 to 2014. Normalized Difference Vegetation Index (NDVI) satellite data at 1-km Results: Five-year annual average NDVI was not associated with percent mammographic density in premenopausal (β = -0.01; 95% CI = -0.03, 0.02; Conclusions: Greenness exposures were not associated with mammographic density. Impact: Prior observations of a protective association between greenness and breast cancer may not be driven by differences in breast tissue composition, as measured by mammographic density, but rather other mechanisms.

Indexed as

BreastGreennessMammographic densityMammographyNatural vegetationNormalized Difference Vegetation Index

Identifiers

PMID35975164
PMCPMC9374192
OpenAlexW4286223791

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.