Evidence map›Paper›PMID 35974928›Full record

ReviewCaspian journal of internal medicine2022

Ophthalmological aspects of mustard gas poisoning (focus on management).

Mehrdad Rafati-Rahimzadeh, Mehravar Rafati-Rahimzadeh, Sohrab Kazemi, Seyedeh Roghieh Jafarian Amiri, Abbas Soleymani, Ali Akbar Moghadamnia

Open access · greenAbstract readReview
In one paragraph

Review in Caspian journal of internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mehrdad Rafati-RahimzadehDepartment of Nursing, Babol University of Medical Sciences, Babol, Iran.
Mehravar Rafati-RahimzadehDepartment of Medical Physics, Kashan University of Medical Sciences, Kashan, Iran.
Sohrab KazemiCancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Seyedeh Roghieh Jafarian AmiriDepartment of Nursing, Babol University of Medical Sciences, Babol, Iran.
Abbas SoleymaniDepartment of Ophthalmology, Babol University of Medical Sciences, Babol, Iran.
Ali Akbar MoghadamniaDepartment of Ophthalmology, Babol University of Medical Sciences, Babol, Iran.
Babol University of Medical Sciences · IRKashan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Amongst the chemical warfare agents, blistering (vesicant) agents can be significant materials. The most important agent in this group is sulfur mustard (mustard gas) which is known as "King of chemical warfare (CW) agents ". Exposure to this agent, seriously causes damages in several organs, such as the eyes. This article reviews the ophthalmological aspects of sulfur mustard with reference of its management. Methods: A wide-ranging search in PubMed databases, Thomson Reuters and Scopus was done and different aspects of chemical properties of sulfur mustard, its mechanism of action and effects on eyes, clinical finding, diagnostic evaluation, initiate actions, pharmaceutical and surgical interventions was reported. Results: Sulfur mustard can alkylate DNA and RNA strands and break down structures of protein and lipid of cell membrane. This may impair cell energy production, and leads to cell death. Exposure to sulfur mustard, therefore, causes such problems for organs, including irreversible damage to the eyes. Conclusion: Understanding the mechanism of the sulfur mustard effect and the early training in prevention injuries will cause fewer complications and damage to organs, including the eyes. Washing the eyes with tap water or eyewash solutions, using mydriatic drops, anti- inflammatory drugs, matrix metalloproteinase inhibitors and antibiotics may help to the management of poisoning. Surgical interventions including tarsorrhaphy, amniotic membrane transplantation, stem cell transplantation and corneal transplantation could reduce the harm to the victims.

Indexed as

AlkylatingBlistering agentsCorneal transplantationkeratoplastyMustard gasSulfur mustardTarsorrhaphy

Identifiers

PMID35974928
PMCPMC9348212
OpenAlexW4302389379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.