Evidence map›Paper›PMID 35974910›Full record

ArticleIndian journal of microbiology2022

Ruijie Meng, Wenya Dong, Jie Gao, Chunrong Lu, Chenchen Zhang, Qinghua Liao, Liang Chen, Huizhong Wu, Jiwen Hu, Wenjing Wei and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Indian journal of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Bioprospecting ofFrontiers in microbiology · 2024
    Review
  6. Article
  7. Biomarker discovery for tuberculosis using metabolomics.Frontiers in molecular biosciences · 2023
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Ruijie Meng *Department of Microbiology and Immunology, College of Basic Medicine and Public Hygiene, Jinan University, GuangZhou, 510632 China.
Wenya Dong *Department of Microbiology and Immunology, College of Basic Medicine and Public Hygiene, Jinan University, GuangZhou, 510632 China.
Jie GaoDepartment of Microbiology and Immunology, College of Basic Medicine and Public Hygiene, Jinan University, GuangZhou, 510632 China.
Chunrong LuShenzhen Center for Chronic Disease Control, Shenzhen, 518102 China.
Chenchen ZhangCenter for Tuberculosis Control of Guangdong Province, Key laboratory of translational medicine of Guangdong, Guangzhou, 510630 China.
Qinghua LiaoCenter for Tuberculosis Control of Guangdong Province, Key laboratory of translational medicine of Guangdong, Guangzhou, 510630 China.
Liang ChenCenter for Tuberculosis Control of Guangdong Province, Key laboratory of translational medicine of Guangdong, Guangzhou, 510630 China.
Huizhong WuCenter for Tuberculosis Control of Guangdong Province, Key laboratory of translational medicine of Guangdong, Guangzhou, 510630 China.
Jiwen HuMedical Laboratory of Shenzhen Luohu Hospital Group, Shenzhen, 518112 China.
Wenjing WeiCenter for Tuberculosis Control of Guangdong Province, Key laboratory of translational medicine of Guangdong, Guangzhou, 510630 China.
Zhenyou JiangDepartment of Microbiology and Immunology, College of Basic Medicine and Public Hygiene, Jinan University, GuangZhou, 510632 China.ORCID 0000-0002-9941-2990
Center for Tuberculosis Control of Guangdong Province · CNJinan University · CNShenzhen Luohu People's Hospital · CNShenzhen Nanshan Center for Chronic Disease Control · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigated the changes of gut microbiome and fecal metabolome during anti-tuberculosis chemotherapy with isoniazid (H)-rifampin (R)-pyrazinamide (Z)-ethambutol (E). Patients and methods: (1) In this study, we recruited 168 stool specimens from 49 healthy volunteers without Results: Mtb infection can reduce the diversity of intestinal flora of ATB patients and change their taxonomic composition, while the diversity of intestinal flora of ATB patients were restored during anti-TB chemotherapy. Especially, family Conclusion: Anti-TB chemotherapy with HRZE can disrupt both gut microbiotas and metabolome in ATB patients. Some specific genera and metabolites are depleted or enriched during anti-TB chemotherapy. Therefore, revealing potential relevance between gut microbiota and anti-TB chemotherapy will provide potential biomarkers for evaluating the therapeutic efficacy in ATB patients. Supplementary Information: The online version contains supplementary material available at 10.1007/s12088-022-01003-2.

Indexed as

16S rRNAAnti-TB chemotherapyFecal metabolomeGut microbiomeTuberculosis

Identifiers

PMID35974910
PMCPMC9375812
OpenAlexW4221006154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.