Evidence map›Paper›PMID 35974896›Full record

ArticleInfection and drug resistance2022

A Cohort Study of Seroprevalence of Antibodies Against SARS-CoV-2 Infection Among Healthcare Workers at a Tertiary Hospital in Saudi Arabia.

Hayat Mushcab, Jaffar A Al-Tawfiq, Mohammed Ghamdi, Amani Babgi, Abdulrazack Amir, Salwa S Sheikh, Adel Darwisheh, Abrar Alobaid, Arulanantham Zechariah Jebakumar, Saeed Qahtani and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04469647 (COVID 19 Antibody Seroprevalence Amongst Healthcare Workers in Johns Hopkins Aramco Healthcare), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04469647 unknown statusnot on this map

COVID 19 Antibody Seroprevalence Amongst Healthcare Workers in Johns Hopkins Aramco Healthcare

TypeobservationalSponsorJohns Hopkins Aramco HealthcareRan2020 to 2021Enrolled1,200ConditionsCOVID 19ArmsSerology Test
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Hayat MushcabResearch Office, Johns Hopkins Aramco Healthcare, Dhahran, Eastern Province, Saudi Arabia.ORCID 0000-0003-4398-7020
Jaffar A Al-TawfiqInfectious Disease Unit - Specialty Internal Medicine, and Quality and Patient Safety Department, Johns Hopkins Aramco Healthcare, Dhahran, Eastern Province, Saudi Arabia.ORCID 0000-0002-5752-2235
Mohammed GhamdiPopulation Health Department, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
Amani BabgiClinical Practice Education & Research, Johns Hopkins Aramco Healthcare, Dhahran, Eastern Province, Saudi Arabia.
Abdulrazack AmirOffice of Academic Affairs, Johns Hopkins Aramco Healthcare, Dhahran, Eastern Province, Saudi Arabia.
Salwa S SheikhPathology Department, Johns Hopkins Aramco Healthcare, Dhahran, Eastern Province, Saudi Arabia.
Adel DarwishehLaboratory Services Department, Johns Hopkins Aramco Healthcare, Dhahran, Eastern Province, Saudi Arabia.
Abrar AlobaidLaboratory Services Department, Johns Hopkins Aramco Healthcare, Dhahran, Eastern Province, Saudi Arabia.
Arulanantham Zechariah JebakumarVice Deanship of Postgraduate Studies Research, Prince Sultan Military College of Health Sciences, Dhahran, Eastern Province, Saudi Arabia.
Saeed QahtaniWellness Institute, Johns Hopkins Aramco Healthcare, Dhahran, Eastern Province, Saudi Arabia.
Ahmed Al SagheirResearch Office, Johns Hopkins Aramco Healthcare, Dhahran, Eastern Province, Saudi Arabia.
Saudi Aramco Medical Services Organization · SAJohns Hopkins University · USPrince Sultan Military College of Health Sciences

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The nature of the healthcare workers' jobs standing at the frontline against the coronavirus disease 2019 (COVID-19) puts them at a higher risk of unknowingly contracting the disease and potentially contributing to the spread. This study aims to assess the overall positive seroconversion prevalence of SARS-CoV-2. Methods: This is a longitudinal cohort study of healthcare workers at Johns Hopkins Aramco Healthcare (JHAH). JHAH is a tertiary hospital located in Dhahran serving patients in several districts in the Eastern Province of Saudi Arabia. Participants were recruited between June and December 2020. Each participant had a serology blood test and completed the World Health Organization's risk factor assessment questionnaire. Results: This study included 682 participants working in JHAH, representing 15.7% of our population. Out of the 682 participants, 15.2% had a positive SARS-CoV-2 rt-PCR before taking part in the study. However, only 87 tested positive for SARS-CoV-2 antibodies, a prevalence of 12.7% of all participants. Out of the 87 positives for SARS-CoV-2 antibodies, 17 participants never tested positive for COVID-19 rt-PCR, a prevalence of 2.9%. Moreover, not properly using alcohol-based hand rub or soap and water after the risk of body fluid exposure and wearing personal protective equipment when indicated were found to be statistically significant to having a positive SARS-CoV-2 IgG assay. Conclusion: Positive seroconversion rate was considerably low during the first wave of COVID-19 amongst JHAH's healthcare workers and similar to other healthcare organizations in Saudi Arabia. Seropositivity correlated significantly with following infection prevention and control recommendations. Clinicaltrialsgov Identifier: NCT04469647.

Indexed as

coronavirus disease-2019COVID-19HCWhealthcare workersprevalenceSARS-CoV-2

Identifiers

PMID35974896
PMCPMC9375977
OpenAlexW4293392648

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.