Evidence map›Paper›PMID 35974693›Full record

ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2023

Increasing numbers and improved overall survival of patients on kidney replacement therapy over the last decade in Europe: an ERA Registry study.

Jilske A Huijben, Anneke Kramer, Julia Kerschbaum, Johan de Meester, Frederic Collart, Olga Lucía Rodríguez Arévalo, Jaakko Helve, Mathilde Lassalle, Runolfur Palsson, Marc Ten Dam and 11 more

Open access · bronzeAbstract read
In one paragraph

Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Incidence and prevalence of kidney replacement therapy in Central and Eastern Europe-trends from the ERA Registry.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Article
  4. Article
  5. Kidney replacement therapy for men and women according to the ERA Registry and the USRDS.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Article
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  9. Review
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  16. Article
  17. Chronic kidney disease.Nature reviews. Disease primers · 2025
    Review
  18. Global Perspectives on Renal Transplantation in Chronic Kidney Disease: A Systematic Review of Adult and Geriatric Populations in Europe and Indonesia.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2025
    Review
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  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 17 institutions in 12 countries.

Jilske A HuijbenDepartment of Medical Informatics, ERA Registry, Amsterdam UMC, Academic Medical Center, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
Anneke KramerDepartment of Medical Informatics, ERA Registry, Amsterdam UMC, Academic Medical Center, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.ORCID 0000-0002-7560-2669
Julia KerschbaumAustrian Dialysis and Transplant Registry, Department of Internal Medicine IV - Nephrology and Hypertension, Medical University Innsbruck, Austria.
Johan de MeesterDepartment of Nephrology, Dialysis and Hypertension, Dutch-speaking Belgian Renal Registry (NBVN), Sint-Niklaas, Belgium.
Frederic CollartFrench-Belgian ESRD Registry (GNFB), Brussels, Belgium.ORCID 0000-0003-1673-5450
Olga Lucía Rodríguez ArévaloValencia Region Renal Registry, Dirección General de Salut Publica i Adiccions, Valencia, Spain.
Jaakko HelveFinnish Registry for Kidney Diseases, Helsinki, Finland.
Mathilde LassalleREIN Registry, Agence de la Biomédecine, Saint-Denis La Plaine, France.
Runolfur PalssonDivision of Nephrology, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland.
Marc Ten DamDutch Registry RENINE, Nefrovisie, Utrecht, The Netherlands.
Anna CasulaUK Renal Registry, the Renal Association, Bristol, UK.
Shona MethvenDepartment of Renal Medicine, Aberdeen Royal Infirmary, Foresterhill Health Campus, Aberdeen, UK.
Alberto OrtizSchool of Medicine, IIS-Fundacion Jimenez Diaz, University Autonoma of Madrid, FRIAT and REDINREN, Madrid, Spain.ORCID 0000-0002-9805-9523
Pietro Manuel FerraroU.O.S. Terapia Conservativa della Malattia Renale Cronica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID 0000-0002-1379-022X
Mårten SegelmarkDepartment of Clinical Sciences, Division of Nephrology, Lund University and Skane University Hospital, Lund, Sweden.
Pablo Ucio MingoCoordinador Autonómico de Trasplantes de Castilla y León, Dirección General de Planificación y Asistencia Sanitaria, Valladolid, Castilla y León, Spain.
Mustafa AriciDepartment of Nephrology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Anna Varberg ReisæterDepartment of Transplantation Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Maria StendahlSwedish Renal Registry, Department of Internal Medicine, Ryhov County Hospital, Jönköping, Sweden.
Vianda S StelDepartment of Medical Informatics, ERA Registry, Amsterdam UMC, Academic Medical Center, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
Kitty J JagerDepartment of Medical Informatics, ERA Registry, Amsterdam UMC, Academic Medical Center, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
Amsterdam UMC Location University of Amsterdam · NLAberdeen Royal Infirmary · GBAgence de la Biomédecine · FRFrench Community of Belgium · BEHacettepe University · TRHospital Universitario Fundación Jiménez Díaz · ESJunta de Castilla y León · ESLund University · SENetherlands Heart Registration · NLOslo University Hospital · NORenal Association · GBRyhov Hospital Jönköping · SEStatistics Austria · ATUniversità Cattolica del Sacro Cuore · ITUniversitat Politècnica de València · ESUniversity of Helsinki · FIUniversity of Iceland · IS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to describe the trends in the incidence, prevalence and survival of patients on kidney replacement therapy (KRT) for end-stage kidney disease (ESKD) across Europe from 2008 to 2017.

methodsData from renal registries in 9 countries and 16 regions that provided individual patient data to the ERA Registry from 2008 to 2017 were included. These registries cover 34% of the general population in Europe. Crude and standardized incidence and prevalence per million population (pmp) were determined. Trends over time were studied using Joinpoint regression. Survival probabilities were estimated using Kaplan-Meier analysis and hazard ratios (HRs) using Cox regression analysis.

resultsThe standardized incidence of KRT was stable [annual percentage change (APC): -1.48 (-3.15; 0.21)] from 2008 (146.0 pmp) to 2011 (141.6 pmp), followed by a slight increase [APC: 1.01 (0.43; 1.60)] to 148.0 pmp in 2017, although trends in incidence varied across countries. This increase was primarily due to a rise in the incidence of KRT in men older than 65 years. Moreover, as a cause of kidney failure, diabetes mellitus is increasing. The standardized prevalence increased from 2008 (990.0 pmp) to 2017 (1166.8 pmp) [APC: 1.82 (1.75; 1.89)]. Patient survival on KRT improved in the time period 2011-13 compared with 2008-[adjusted HR: 0.94 (0.93; 0.95)].

conclusionThis study showed an overall increase in the incidence and prevalence of KRT for ESKD as well as an increase in the KRT patient survival over the last decade in Europe.

Indexed as

Kidney Failure, ChronicRenal Replacement TherapyEuropeHumansIncidenceMaleProportional Hazards ModelsRegistriesdialysisincidencekidney transplantationprevalencesurvival

Identifiers

PMID35974693
PMCPMC10064979
OpenAlexW4292295573

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.