ReviewEuropean journal of cancer care2022
Hepatocellular carcinoma and its impact on quality of life: A review of the qualitative literature.
Review in European journal of cancer care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Health-related quality of life in patients with unresectable hepatocellular carcinoma treated with SIRT and nivolumab: a sub-analysis of the NASIR-HCC trial.Journal of patient-reported outcomes · 2025Trial
- Dynamic changes in frailty and related factors in older patients with liver cancer: A latent transition analysis approach.Asia-Pacific journal of oncology nursing · 2026Article
- Quality of life in patients with hepatocellular carcinoma: a bibliometric analysis.Discover oncology · 2026Article
- Healthcare system complexity of hepatitis B and C related liver disease: service mapping in New South Wales, Australia.Frontiers in health services · 2026Article
- HEALTH-RELATED QUALITY OF LIFE IN CHRONIC LIVER DISEASE: CLINICAL BURDEN, DETERMINANTS, AND IMPLICATIONS FOR PATIENT-CENTERED CARE.Arquivos de gastroenterologia · 2026Review
- From Fear to Adaptation: The Journey of Patients with Liver Cancer Living with the Fear of Cancer Recurrence.Current oncology (Toronto, Ont.) · 2025Article
- Qualitative research to understand the patient experience with advanced and/or metastatic hepatocellular carcinoma.Hepatic oncology · 2025Article
- End-of-life in Hepatocellular Carcinoma: How Palliative Care and Social Factors Impact Care and Cost.Journal of clinical gastroenterology · 2025Article
- Predictors of long-term survival outcomes of patients with hepatocellular carcinoma without recurrence at five years after liver resection.Langenbeck's archives of surgery · 2025Article
- Timing and Method of Patient-Provider Communication for Abnormal Hepatocellular Carcinoma Screening Results in Cirrhosis.JCO clinical cancer informatics · 2025Article
- Cancer stem cells in hepatocellular carcinoma: therapy resistance and emerging treatments.Frontiers in immunology · 2025Review
- Improving Health-Related Quality of Life in Hepatocellular Carcinoma Patients: Key Methodologies for Assessing Patient Reported Outcomes and Intervention Targets.Journal of hepatocellular carcinoma · 2025Review
- Health-Related Quality of Life in Patients with Hepatocellular Carcinoma Post-Surgery: A Scoping Review.International journal of medical sciences · 2025Article
- Tislelizumab versus Sorafenib in First-Line Treatment of Unresectable Hepatocellular Carcinoma: Impact on Health-Related Quality of Life in RATIONALE-301 Study.Liver cancer · 2024Article
- Patient Experience of Hepatocellular Carcinoma and Their Treatment Goals: An International Qualitative Study and Patient Journey Map.Advances in therapy · 2024Article
- Cancer stigma: the need for policy and programmatic action.Journal of the National Cancer Institute. Monographs · 2024Article
- Stigmatization of drinking patients with liver cancer: The role of socioeconomic status.Heliyon · 2024Article
- Article
- Immunotherapy for the treatment of hepatocellular carcinoma: finally in clinical practice.Hepatobiliary surgery and nutrition · 2023Article
- Mini-organs with big impact: Organoids in liver cancer studies.Oncology research · 2023Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionHepatocellular carcinoma (HCC) carries significant burden of disease, with high mortality rates and poor prognosis. It is therefore important to consider quality of life (QoL) for patients with HCC. Quantitative research assesses HCC and QoL via standardised measurement tools, but these do not capture the full scope of patient experiences. This review examines the body of qualitative research on this topic, to develop a comprehensive understanding of QoL for this population.
methodsMedline, EMBASE and PsycINFO were systematically searched with keywords relating to HCC, QoL and patient experience. After applying inclusion and exclusion criteria, key findings of included studies were extracted and analysed for themes.
resultsEleven studies were included for thematic analysis, with five themes identified as central to QoL: (1) burden of physical symptoms and treatment side effects; (2) psychological impact and coping strategies; (3) social function and stigma; (4) spiritual wellbeing, sense of self and meaning of illness and (5) pervasive uncertainty.
conclusionHCC profoundly impacted patients' lives, spanning physical, psychological, social and spiritual QoL domains. While QoL was reduced overall, some features of patient experiences that enhanced QoL were noted. The findings complement data from quantitative studies, helping to build a richer understanding of QoL.
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