Evidence map›Paper›PMID 35974455›Full record

ArticleActa ophthalmologica2023

Pupil diameter during cataract surgery after intracameral injection of the first ready-to-use combination of mydriatics and anaesthetic at the beginning of surgery in patients with a preoperative pupil diameter <6 mm.

Dariusz Kęcik, Iwona Grabska-Liberek, Piotr Jurowski, Ewa Mrukwa-Kominek, Wojciech Omulecki, Bożena Romanowska-Dixon, Jacek P Szaflik, Wanda Romaniuk, Jerzy Szaflik, Dorota Kopacz and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Acta ophthalmologica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Dariusz KęcikDepartment of Ophthalmology, Medical University of Warsaw, Warsaw, Poland.ORCID https://orcid.org/0000-0002-2966-4172
Iwona Grabska-LiberekDepartment of Ophthalmology, Medical Centre for Postgraduate Education, Warsaw, Poland.
Piotr JurowskiDepartment of Eye Diseases, Medical University of Lodz, Lodz, Poland.
Ewa Mrukwa-KominekDepartment of Ophthalmology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.
Wojciech OmuleckiDepartment of Ophthalmology, Medical University of Lodz, University Hospital No 1, Lodz, Poland.
Bożena Romanowska-DixonDepartment of Ophthalmology and Ocular Oncology, Jagiellonian University Medical College, Cracow, Poland.
Jacek P SzaflikDepartment of Ophthalmology, Medical University of Warsaw, Warsaw, Poland.
Wanda RomaniukDepartment of Ophthalmology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.
Jerzy SzaflikDepartment of Ophthalmology, Medical University of Warsaw, Warsaw, Poland.
Dorota KopaczDepartment of Ophthalmology, Medical University of Warsaw, Warsaw, Poland.
Katarzyna MianowskaDepartment of Ophthalmology, Medical University of Warsaw, Warsaw, Poland.
Medical University of Warsaw · PLMedical University of Lodz · PLMedical University of Silesia · PLJagiellonian University · PLPostgraduate School of Molecular Medicine · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe evaluated, in a real-life setting, the effect of Mydrane® (ready-to-use combination of tropicamide, phenylephrine hydrochloride and lidocaine, injected into the anterior chamber at the beginning of cataract surgery to induce mydriasis and intraocular anaesthesia) on the pupil diameter during cataract surgery in patients with a preoperative pupil diameter <6 mm after the use of topical mydriatics.

methodsWe collected and analysed the data of 59 consecutive patients whose pupils dilated to a diameter <6 mm after the administration of mydriatic eye drops during the preoperative visit and who received Mydrane® during cataract surgery.

resultsIn the group of 59 patients with a preoperative pupil diameter <6 mm after topical mydriatics, cataract surgery was performed in 36 patients (61.0%) using only Mydrane® to obtain mydriasis, with no additional drug or medical device. The mean pupil diameters in this group (36 of 59) during the preoperative assessment after topical mydriatics and just before capsulorhexis when Mydrane® was injected during surgery were 5.1 ± 0.74 and 6.15 ± 1.14 mm. Additional drugs were used in 23 patients (39%). In this group, the mean pupil diameters after topical mydriatics and just before capsulorhexis using Mydrane® were 4.58 ± 1.06 and 5.6 ± 1.26 mm, respectively.

conclusionIn a real-life setting, the mean pupil diameter achieved during cataract surgery after the intracameral injection of Mydrane® in patients with a preoperative pupil diameter <6 mm was over 1 mm larger than the mean pupil diameter after topical mydriatics, despite the trauma caused by the operation.

Indexed as

AnestheticsCataractMydriasisPhacoemulsificationHumansLidocaineMydriaticsOphthalmic SolutionsPhenylephrineTropicamideAnestheticsLidocaineMydriaticsOphthalmic SolutionsPhenylephrineTropicamidecataract surgeryintracameral mydriaticsMydranephenylephrinesmall pupiltropicamide

Identifiers

PMID35974455
PMCPMC10087216
OpenAlexW4292295018

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.