Evidence map›Paper›PMID 35974361›Full record

ArticleBMC oral health2022

Efficacy of chitosan paste as intracanal medication against Enterococcus faecalis and Candida albicans biofilm compared with calcium hydroxide in an in vitro root canal infection model.

Pasika Thienngern, Anchana Panichuttra, Chootima Ratisoontorn, Chuanchom Aumnate, Oranart Matangkasombut

Open access · goldAbstract read
In one paragraph

Article in BMC oral health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. CombatingJournal of conservative dentistry and endodontics · 2026
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  8. Review
  9. Comparative evaluation of antibacterial efficacy ofJournal of conservative dentistry and endodontics · 2024
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  10. Article
  11. Leaf Extracts ofTheScientificWorldJournal · 2024
    Article
  12. Article
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Pasika ThienngernDepartment of Operative Dentistry, Faculty of Dentistry, Chulalongkorn University, 34 Henri- Dunant Road, Wangmai, Patumwan, Bangkok, 10330, Thailand.
Anchana PanichuttraDepartment of Operative Dentistry, Faculty of Dentistry, Chulalongkorn University, 34 Henri- Dunant Road, Wangmai, Patumwan, Bangkok, 10330, Thailand. anchana.p@chula.ac.th.
Chootima RatisoontornDepartment of Operative Dentistry, Faculty of Dentistry, Chulalongkorn University, 34 Henri- Dunant Road, Wangmai, Patumwan, Bangkok, 10330, Thailand.
Chuanchom AumnateMetallurgy and Materials Science Research Institute, Chulalongkorn University, Soi Chula 12, Phayathai Road, Pathumwan, Bangkok, 10330, Thailand.
Oranart MatangkasombutDepartment of Microbiology and Center of Excellence on Oral Microbiology and Immunology, Faculty of Dentistry, Chulalongkorn University, 34 Henri- Dunant Road, Wangmai, Patumwan, Bangkok, 10330, Thailand. oranart.m@chula.ac.th.
Chulalongkorn University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnterococcus faecalis and Candida albicans are frequently found in persistent endodontic infection and could remain in dentinal tubules despite intracanal medication with calcium hydroxide (Ca(OH)

methodsThirty-six sterilized human root samples prepared from extracted premolars and upper maxillary incisors were infected with E. faecalis for 14 days, while 32 were infected with C. albicans for 48 h, for mature biofilm formation. The samples were assigned to 6 groups of intracanal medications: Group 1: no medication (negative control); Group 2: 20% Polyethylene glycol (PEG); Group 3: 20% Propylene glycol (PG); Group 4: Ca(OH)

resultsFor E. faecalis, chitosan + PG had significantly higher antibacterial activity than Ca(OH)

conclusionChitosan paste showed better efficacy in reducing viable E. faecalis biofilm when compared to Ca(OH)

Indexed as

Anti-Infective AgentsChitosanAgarAnti-Bacterial AgentsBiofilmsCalcium HydroxideCandida albicansDental Pulp CavityEnterococcus faecalisHumansRoot Canal IrrigantsAgarAnti-Bacterial AgentsAnti-Infective AgentsCalcium HydroxideChitosanRoot Canal IrrigantsCandida albicansChitosanEnterococcus faecalisIntracanal medicationPolyethylene glycolPropylene glycol

Identifiers

PMID35974361
PMCPMC9382833
OpenAlexW4292179975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.