ArticlePediatric research2023
Body composition and bone mass among 5-year-old survivors of necrotizing enterocolitis.
Article in Pediatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 8 citations in OpenAlex.
- Chronic Intestinal Failure During the Neonatal Period Related to Height at Five Years of Age.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- DXA-Derived Body Composition and Insulin Resistance at Preschool Age in Very-Low-Birth-Weight Preterm Infants: A Prospective Cohort Study.Diagnostics (Basel, Switzerland) · 2026Article
- Longitudinal course of bone health from infancy to mid-adulthood in preterm and term-born individuals.Scientific reports · 2025Article
- Ultrasound for the Early Detection and Diagnosis of Necrotizing Enterocolitis: A Scoping Review of Emerging Evidence.Diagnostics (Basel, Switzerland) · 2025Review
- The Long-Term Impact of Preterm Birth on Metabolic Bone Profile and Bone Mineral Density in Childhood.Metabolites · 2025Article
- Unexplained gut symptoms in extremely preterm infants are associated with gastrointestinal dysfunction at 5.5 years.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Recent advances in understanding pathophysiology of non-nutritional stunting in very preterm infants.Clinical and experimental pediatrics · 2025Article
- Gut microbiota differences in five-year-old children that were born preterm with a history of necrotizing enterocolitis: A pilot trial.iScience · 2024Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNecrotizing enterocolitis (NEC) affects the intestine of preterm infants. Preterm infants risk inadequate bone mineralization. This risk may increase if the intestinal uptake of minerals is affected after NEC.
methodsThis is a study of growth, bone mineral density (BMD), bone mineral content (BMC), and body composition at 5 years of age among Swedish children born before gestational week 37 + 0 with a history of NEC, minimum stage IIA, compared to matched controls. Fifty children, 25 NEC cases and 25 controls, were examined with dual energy X-ray absorptiometry (DXA) and DXA with laser.
resultsThe NEC cases had lower weight, -1.3 SDS vs -0.7 SDS, a lower fat mass and fat percent, 23.4 vs 29.1%, compared to the controls. NEC cases had lower BMC total body head excluded, 355.6 g vs 416.7 g. BMD Z-scores were lower among NEC cases in total body head excluded, -0.7 vs -0.1, and in lumbar spine.
conclusionsPreterm NEC survivors at 5 years of age had reduced growth, an altered body composition, and indications of a lower bone mass compared to matched controls. The study suggests that preterm infants diagnosed with NEC need special attention during childhood regarding growth and bone health. IMPACT: A follow-up longitudinal study of growth, bone health, and body composition at 5 years of age among children born preterm with a history of NEC compared to matched controls. The NEC cases had lower weight than controls. NEC cases had an altered body composition with lower fat mass compared to controls. The DXA results showed that the NEC cases had lower bone mineral content and a tendency to lower bone mineral density. The study suggests that preterm infants diagnosed with NEC need special attention at follow-up regarding growth and bone health compared to preterm infants without NEC.
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