Evidence map›Paper›PMID 35974082›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2022

Changes in preterm birth during the COVID-19 pandemic by duration of exposure and race and ethnicity.

Anne M Mullin, Sara C Handley, Lisbet Lundsberg, Michal A Elovitz, Scott A Lorch, Elias J McComb, Diana Montoya-Williams, Nancy Yang, Kevin Dysart, Moeun Son and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Anne M MullinTufts University School of Medicine, Boston, MA, USA.ORCID 0000-0002-4803-3667
Sara C HandleyDivision of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0001-8436-4351
Lisbet LundsbergDepartment of Obstetrics, Gynecology, and Reproductive Science, Yale University, New Haven, CT, USA.
Michal A ElovitzDepartment of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.ORCID 0000-0001-7554-7180
Scott A LorchDivision of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Elias J McCombDepartment of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
Diana Montoya-WilliamsDivision of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Nancy YangDivision of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Kevin DysartDivision of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0003-2715-2293
Moeun SonDepartment of Obstetrics, Gynecology, and Reproductive Science, Yale University, New Haven, CT, USA.
Jay GreenspanDivision of Neonatology, Nemours duPont Pediatrics, Philadelphia, PA, USA.
Jennifer F CulhaneDepartment of Obstetrics, Gynecology, and Reproductive Science, Yale University, New Haven, CT, USA.
Heather H BurrisDivision of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA. burrish@chop.edu.ORCID 0000-0003-4510-9547
Children's Hospital of Philadelphia · USYale University · USUniversity of Pennsylvania · USDuPont (United States) · USPennsylvania Department of Health · USTufts University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI A. Clementina Mesaros · 2006 to 2026
$35.3M
Maternal Resilience to Stress, Neonatal Outcomes, and Racial/Ethnic Health DisparitiesK23HD102526 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI MONTOYA-WILLIAMS, DIANA C · 2021 to 2025
$793k
NCATS NIH HHS UL1 TR001863NICHD NIH HHS K23 HD102526NIEHS NIH HHS P30 ES013508U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) K23HD102526
6 · The paper itself

Abstract

objectiveWe aimed to determine whether coronavirus-disease-2019 (COVID-19) pandemic exposure duration was associated with PTB and if the pandemic modified racial disparities. STUDY

designWe analyzed Philadelphia births and replicated in New Haven. Compared to matched months in two prior years, we analyzed overall PTB, specific PTB phenotypes, and stillbirth.

resultsOverall, PTB was similar between periods with the following exceptions. Compared to pre-pandemic, early pregnancy (<14 weeks') pandemic exposure was associated with lower risk of PTB < 28 weeks' (aRR 0.60 [0.30-1.10]) and later exposure with higher risk (aRR 1.77 [0.78-3.97]) (interaction p = 0.04). PTB < 32 weeks' among White patients decreased during the pandemic, resulting in non-significant widening of the Black-White disparity from aRR 2.51 (95%CI: 1.53-4.16) to aRR 4.07 (95%CI: 1.56-12.01) (interaction P = 0.41). No findings replicated in New Haven.

conclusionWe detected no overall pandemic effects on PTB, but potential indirect benefits for some patients which could widen disparities remains possible.

Indexed as

COVID-19Premature BirthEthnicityFemaleHumansInfant, NewbornPandemicsPregnancyRisk Factors

Identifiers

PMID35974082
PMCPMC9379882
OpenAlexW4291972375

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.