ArticleScientific reports2022
Light color efficiency-balanced trans-palpebral illumination for widefield fundus photography of the retina and choroid.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 22 citations in OpenAlex.
- High dynamic range widefield fundus photography with transcranial illumination: a contrast agent-free method for non-mydriatic choroidal imaging.Biomedical optics express · 2025Article
- Affordable ultra-widefield smartphone PedCam for comprehensive pediatric retinal examination.Biomedical optics express · 2024Article
- Retinal imaging and Alzheimer's disease: a future powered by Artificial Intelligence.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Review
- Assessing spectral effectiveness in color fundus photography for deep learning classification of retinopathy of prematurity.Journal of biomedical optics · 2024Article
- Multispectral Fundus Photography of Choroidal Nevi With Trans-Palpebral Illumination.Translational vision science & technology · 2024Article
- Multispectral Fundus Photography of Choroidal Nevi with Trans-Palpebral Illumination.medRxiv : the preprint server for health sciences · 2024Article
- Preserving polarization maintaining photons for enhanced contrast imaging of the retina.Biomedical optics express · 2023Article
- Evaluating spatial dependency of the spectral efficiency in trans-palpebral illumination for widefield fundus photography.Biomedical optics express · 2023Article
- Portable widefield fundus camera with high dynamic range imaging capability.Biomedical optics express · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
A wide-field fundus camera, which can selectively evaluate the retina and choroid, is desirable for better detection and treatment evaluation of eye diseases. Trans-palpebral illumination has been demonstrated for wide-field fundus photography, but its application for true-color retinal imaging is challenging due to the light efficiency delivered through the eyelid and sclera is highly wavelength dependent. This study is to test the feasibility of true-color retinal imaging using efficiency-balanced visible light illumination, and to validate multiple spectral imaging (MSI) of the retina and choroid. 530 nm, 625 nm, 780 nm and 970 nm light emission diodes (LED)s are used to quantitatively evaluate the spectral efficiency of the trans-palpebral illumination. In comparison with 530 nm illumination, the 625 nm, 780 nm and 970 nm light efficiencies are 30.25, 523.05, and 1238.35 times higher. The light efficiency-balanced 530 nm and 625 nm illumination control can be used to produce true-color retinal image with contrast enhancement. The 780 nm light image enhances the visibility of choroidal vasculature, and the 970 nm image is predominated by large veins in the choroid. Without the need of pharmacological pupillary dilation, a 140° eye-angle field of view (FOV) is demonstrated in a snapshot fundus image. In coordination with a fixation target, the FOV can be readily expanded over the equator of the eye to visualize vortex ampullas.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.