Evidence map›Paper›PMID 35973945›Full record

ArticleJournal of medical radiation sciences2022

Pencil-beam scanning proton therapy for the treatment of glomus jugulare tumours.

Jiří Kubeš, Vladimír Vondráček, Michal Andrlik, Matěj Navrátil, Silvia Sláviková, Daniel Klika, Alexandra Haas, Kateřina Dědečková, Kateřina Kopečková, Barbora Ondrová and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of medical radiation sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Jiří KubešProton Therapy Centre Czech, Prague, Czech Republic.
Vladimír VondráčekProton Therapy Centre Czech, Prague, Czech Republic.
Michal AndrlikProton Therapy Centre Czech, Prague, Czech Republic.ORCID https://orcid.org/0000-0001-6581-5583
Matěj NavrátilProton Therapy Centre Czech, Prague, Czech Republic.
Silvia SlávikováProton Therapy Centre Czech, Prague, Czech Republic.
Daniel KlikaProton Therapy Centre Czech, Prague, Czech Republic.
Alexandra HaasProton Therapy Centre Czech, Prague, Czech Republic.
Kateřina DědečkováProton Therapy Centre Czech, Prague, Czech Republic.
Kateřina KopečkováDepartment of Oncology, 2nd Faculty of Medicine, Charles University Prague and Motol University Hospital, Prague, Czech Republic.
Barbora OndrováProton Therapy Centre Czech, Prague, Czech Republic.
Eliška RotnáglováProton Therapy Centre Czech, Prague, Czech Republic.
Štěpán VinakurauProton Therapy Centre Czech, Prague, Czech Republic.
Alexander GrebenyukDepartment of Health Protection and Disaster Medicine, Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Russia.
Jozef RosinaDepartment of Health Care Disciplines and Population Protection, Faculty of Biomedical Engineering, Czech Technical University Prague, Kladno, Czech Republic.
Charles University · CZProton Therapy Centre · CZFirst Pavlov State Medical University of St. Petersburg · RU

Funding

European Regional Development Fund CZ.02.1.01/0.0/0.0/16_019/0000766
6 · The paper itself

Abstract

introductionGlomus jugulare tumours (GJT) are benign tumours that arise locally and destructively in the base of the skull and can be successfully treated with radiotherapy. Patients have a long-life expectancy and the late effects of radiotherapy can be serious. Proton radiotherapy reduces doses to critical organs and can reduce late side effects of radiotherapy. The aim of this study was to report feasibility and early clinical results of 12 patients treated using proton therapy.

methodsBetween December 2013 and June 2019, 12 patients (pts) with GJT (median volume 20.4 cm

resultsAll patients finished treatment without interruption, with excellent dosimetric parameters and mild acute toxicity. Stabilisation of tumour size was detected on MRI in all patients. No changes in symptoms were observed in comparison with pre-treatment conditions. No late effects of radiotherapy were observed.

conclusionPencil-beam scanning proton radiotherapy is highly feasible in the treatment of large GJT with mild acute toxicity and promising short-term results. Longer follow-up and larger patient cohorts are required to further identify the role of pencil-beam scanning (PBS) for this indication.

Indexed as

Glomus Jugulare TumorProton TherapyRadiotherapy, Intensity-ModulatedHumansProtonsRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRetrospective StudiesProtonsglomus jugulareHead and neckproton radiotherapyradiation oncology

Identifiers

PMID35973945
PMCPMC9714513
OpenAlexW4292169412

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.