Evidence map›Paper›PMID 35973922›Full record

ArticleCardiovascular revascularization medicine : including molecular interventions2023

Readmission and In-Hospital Outcomes After Transcatheter Aortic Valve Replacement in Patients With Dementia.

Dae Yong Park, Muhammad Khawar Sana, Sami Shoura, Hasan Hammo, Jiun-Ruey Hu, John K Forrest, Angela Lowenstern, Michael Cleman, Yousif Ahmad, Michael G Nanna

Open access · greenAbstract read
In one paragraph

Article in Cardiovascular revascularization medicine : including molecular interventions, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Dae Yong ParkDepartment of Medicine, Cook County Health, Chicago, IL, USA.
Muhammad Khawar SanaDepartment of Medicine, Cook County Health, Chicago, IL, USA.
Sami ShouraDepartment of Medicine, Cook County Health, Chicago, IL, USA.
Hasan HammoDepartment of Medicine, Cook County Health, Chicago, IL, USA.
Jiun-Ruey HuSection of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT, USA.
John K ForrestSection of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT, USA.
Angela LowensternDivision of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Michael ClemanSection of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT, USA.
Yousif AhmadSection of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT, USA.
Michael G NannaSection of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT, USA. Electronic address: michael.nanna@yale.edu.
Yale University · USCook County Health and Hospitals System · USVanderbilt University Medical Center · US

Funding

Generating novel predictive models to estimate the risk of future ASCVD & Dementia in older adultsR03AG074067 · NIA · YALE UNIVERSITY · PI NANNA, MICHAEL · 2021 to 2022
$335k
NIA NIH HHS R03 AG074067
6 · The paper itself

Abstract

background/purposeThe prevalence of dementia and aortic stenosis (AS) increases with each decade of age. Transcatheter aortic valve replacement (TAVR) is a definitive treatment for AS, but there are scarce data on morbidity, mortality, and readmission risk after TAVR in patients with dementia. METHODS/MATERIALS: We identified all admissions for TAVR in patients with AS in the National Readmissions Database in 2017-2018 and stratified them according to the presence or absence of a secondary diagnosis of dementia. Inpatient outcomes were compared using logistic regression. Cox proportional-hazards models were used to compare 30-, 60-, and 90-day readmissions.

resultsA total of 48,923 index hospitalizations for TAVR were identified, of which 2192 (4.5 %) had a secondary diagnosis of dementia. Presence of dementia was associated with higher odds of delirium, pacemaker placement, acute kidney injury, and fall in hospital. The hazard of 30-day readmission was not significantly different between patients with and without dementia, but patients with dementia experienced a higher hazard of 60-day readmission (HR 1.15, 95 % CI 1.03-1.26, p = 0.011) in the unadjusted model and higher hazard of 90-day readmission in both unadjusted (HR 1.18, 95 % CI 1.08-1.30, p < 0.001) and adjusted models (aHR 1.14, 95 % CI 1.04-1.25, p = 0.004).

conclusionsPatients with dementia who undergo TAVR are at higher risk of in-hospital adverse outcomes and 60- and 90-day readmissions compared with patients without dementia. These estimates should be integrated into shared decision-making discussions with patients and families.

Indexed as

Aortic Valve StenosisDementiaTranscatheter Aortic Valve ReplacementAortic ValveHospitalsHumansPatient ReadmissionRisk FactorsTreatment OutcomeAortic stenosisDementiaReadmissionTAVITAVR

Identifiers

PMID35973922
PMCPMC10940024
OpenAlexW4291034553

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.