Evidence map›Paper›PMID 35973797›Full record

ArticleAmerican journal of perinatology2024

Severe Neonatal Opioid Withdrawal Requiring Pharmacotherapy: Impact of Region of Residence.

Deepika Sankaran, Shikha Rawat, Jennifer L Kachelmeyer, Emily S Li, Anne M Reynolds, Munmun Rawat, Praveen Chandrasekharan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of perinatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Deepika SankaranDivision of Neonatology, Department of Pediatrics, University at Buffalo, Buffalo, New York.ORCID 0000-0002-6704-6949
Shikha RawatDepartment of Economics, Stony Brook University, Stony Brook, New York.
Jennifer L KachelmeyerDivision of Neonatology, Department of Pediatrics, University at Buffalo, Buffalo, New York.ORCID 0000-0002-0940-7881
Emily S LiDivision of Neonatology, Department of Pediatrics, University at Buffalo, Buffalo, New York.
Anne M ReynoldsDivision of Neonatology, Department of Pediatrics, University at Buffalo, Buffalo, New York.
Munmun RawatDivision of Neonatology, Department of Pediatrics, University at Buffalo, Buffalo, New York.
Praveen ChandrasekharanDivision of Neonatology, Department of Pediatrics, University at Buffalo, Buffalo, New York.
University at Buffalo, State University of New York · USAmerican Express (United States) · US

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
UB Clinical Scholar Program in Implementation Science to Achieve Triple AimsK12HL138052 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CANTY, JOHN M, SINGH, RANJIT · 2017 to 2021
$3.1M
Optimizing Chest Compressions for Bradycardia during Neonatal ResuscitationR01HD104909 · NICHD · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CHANDRASEKHARAN, PRAVEEN · 2021 to 2025
$1.5M
Optimizing Transition with Delayed Umbilical Cord Clamping and Supplemental Oxygen during Preterm Resuscitation with Perinatal AsphyxiaR03HD096510 · NICHD · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CHANDRASEKHARAN, PRAVEEN · 2019 to 2020
$160k
NCATS NIH HHS UL1 TR001412NHLBI NIH HHS K12 HL138052NICHD NIH HHS R01 HD104909NICHD NIH HHS R03 HD096510
6 · The paper itself

Abstract

objectivesOur objective was to evaluate the trend and to assess the impact of maternal region of residence in Western New York (WNY), on severe neonatal opioid withdrawal syndrome (NOWS). STUDY

designTerm infants' born at gestational age greater than or equal to 37 weeks with severe NOWS, defined as withdrawal resulting in the receipt of pharmacologic therapy from WNY admitted to our neonatal intensive care unit (NICU) from January 1, 2008 to December 31, 2016, were included. Severe NOWS admissions to our NICU from the following five regions were controlled with birth and insurance data: (1) Urban North, (2) Erie Coastal, (3) Niagara Frontier, (4) Southern Tier, and (5) Urban South.

results"Urban South" residence was associated with an increased risk of severe NOWS (adjusted odds ratio = 1.8, 97.5% confidence interval: 1.1-2.9). The trend in admission for severe NOWS doubled between 2008 to 2010 and 2014 to 2016 (

conclusionIn WNY, neonates born to mothers from the "Urban South" were twice at risk of being admitted for severe NOWS. One-third of infants with severe NOWS after nonprescribed opioid use were placed in foster care. Implementing targeted strategies at the community level may help improve outcomes in NOWS. KEY POINTS: · Maternal region of residence is a risk factor for severe neonatal opioid withdrawal.. · Admissions for severe neonatal opioid withdrawal trended up from 2008 to 2010 to 2014 to 2016.. · One-third of the infants born to mothers on nonprescribed opioids were discharged to foster care..

Indexed as

Intensive Care Units, NeonatalNeonatal Abstinence SyndromeOpioid-Related DisordersAdultAnalgesics, OpioidFemaleHumansInfant, NewbornLogistic ModelsMaleNew YorkOpiate Substitution TreatmentPregnancyResidence CharacteristicsRetrospective StudiesRisk FactorsAnalgesics, Opioid

Identifiers

PMID35973797
PMCPMC11967340
OpenAlexW4293507290

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.