Evidence map›Paper›PMID 35973539›Full record

ArticleThe Science of the total environment2022

Sewage surveillance of SARS-CoV-2 at student campus residences in the Western Cape, South Africa.

Noluxabiso Mangwana, Edward Archer, Christo J F Muller, Wolfgang Preiser, Gideon Wolfaardt, Barbara Kasprzyk-Hordern, Alno Carstens, Ludwig Brocker, Candice Webster, David McCarthy and 5 more

Abstract read
In one paragraph

Article in The Science of the total environment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Noluxabiso MangwanaBiomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg, Cape Town 7505, South Africa; Department of Microbiology, Stellenbosch University, Stellenbosch 7600, South Africa.
Edward ArcherDepartment of Microbiology, Stellenbosch University, Stellenbosch 7600, South Africa.
Christo J F MullerBiomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg, Cape Town 7505, South Africa; Division of Medical Physiology, Faculty of Medicine and Health Sciences, Centre for Cardiometabolic Research in Africa, Stellenbosch University, South Africa.
Wolfgang PreiserDivision of Medical Virology, Faculty of Medicine & Health Sciences, Stellenbosch University, Tygerberg, Cape Town 7505, South Africa; National Health Laboratory Services, Tygerberg Hospital, Tygerberg, Cape Town 7505, South Africa.
Gideon WolfaardtDepartment of Microbiology, Stellenbosch University, Stellenbosch 7600, South Africa; Department of Chemistry and Biology, Ryerson University, Toronto, ON M5B 2K3, Canada.
Barbara Kasprzyk-HordernDepartment of Chemistry, Faculty of Science, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom.
Alno CarstensDepartment of Microbiology, Stellenbosch University, Stellenbosch 7600, South Africa.
Ludwig BrockerDepartment of Microbiology, Stellenbosch University, Stellenbosch 7600, South Africa.
Candice WebsterEnvironment and Health Research Unit, South African Medical Research Council (SAMRC), Johannesburg, South Africa.
David McCarthyEnvironmental and Public Health Microbiology Lab (EPHM LAB), Monash Infrastructure Institute, Department of Civil Engineering, Monash University, Clayton 3800, Australia.
Renee StreetEnvironment and Health Research Unit, South African Medical Research Council (SAMRC), Durban, South Africa.
Angela MatheeEnvironment and Health Research Unit, South African Medical Research Council (SAMRC), Johannesburg, South Africa.
Johan LouwBiomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg, Cape Town 7505, South Africa.
Mongezi MdhluliChief Research Operations Office, South African Medical Research Council, Tygerberg 7050, South Africa.
Rabia JohnsonBiomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg, Cape Town 7505, South Africa; Division of Medical Physiology, Faculty of Medicine and Health Sciences, Centre for Cardiometabolic Research in Africa, Stellenbosch University, South Africa. Electronic address: rabia.johnson@mrc.ac.za.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic capacity is limited in defined communities, posing a challenge in tracking and tracing new infections. Monitoring student residences, which are considered infection hotspots, with targeted wastewater surveillance is crucial. This study evaluated the efficacy of SARS-CoV-2 targeted wastewater surveillance for outbreak mitigation at Stellenbosch University's student residences in South Africa. Using torpedo-style passive sampling devices, wastewater samples were collected biweekly from manholes at twelve Stellenbosch University Tygerberg (SUT) campus and Stellenbosch University-Main (SUM) campus student residences. The surveillance led to an early warning detection of SARS-CoV-2 presence on campus, followed by an informed management strategy leading to restriction of student activities on campus and a delay in the onset of the third wave that was experienced throughout the country. Moreover, the study highlighted the extent of possible infections at defined locations even when a low number of confirmed coronavirus disease 2019 (COVID-19) cases were reported. The study also tracked the surge of the Delta and Omicron variants in the student residences using the Thermo Fisher TaqMan® RT-qPCR genotyping assay.

Indexed as

COVID-19SARS-CoV-2HumansSewageSouth AfricaStudentsWastewaterWastewater-Based Epidemiological MonitoringSewageWastewaterCOVID-19InstitutionNear-source WBEPassive samplingSARS-CoV-2Student campus residencesWastewaterWastewater-based epidemiology

Identifiers

PMID35973539
PMCPMC9375247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.