ReviewAmerican journal of obstetrics and gynecology2023
Placental pathology is necessary to understand common pregnancy complications and achieve an improved taxonomy of obstetrical disease.
Review in American journal of obstetrics and gynecology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 117 citations in OpenAlex.
- Pooled it
- Urinary oxidative stress biomarkers are associated with preterm birth: an Environmental Influences on Child Health Outcomes program study.American journal of obstetrics and gynecology · 2023Pooled it
- Placental basal plate with attached myofibers and adverse pregnancy outcomes: A systematic scoping review.Acta obstetricia et gynecologica Scandinavica · 2026Article
- Abnormal Intrapartum Cardiotocographic Tracing, Fetal Outcome and Placental Pathology.Diagnostics (Basel, Switzerland) · 2026Article
- Successful Delivery Following Ex Vivo Organoid Drug Testing for Unexplained Recurrent Pregnancy Loss.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2026Article
- First-Trimester Maternal CALLY Index Is Associated With Fetal Growth Restriction.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Article
- Article
- Adverse pregnancy outcomes are associated with cardiovascular and renal dysregulation in late pregnancy.BMC pregnancy and childbirth · 2026Article
- Nodular fibromuscular villous stromal dysplasia (NFMVSD): forensic insights into fetal/neonatal outcomes.Pathologica · 2026Article
- Article
- Biologically Inspired Digital Histology for Deep Phenotyping of Placental Composition Changes Across Major Lesion Types.bioRxiv : the preprint server for biology · 2025Article
- Expression of Bax and Bcl-2 in the placenta from pre-term, term, and post-term deliveries: immunohistochemical analysis.Medical molecular morphology · 2025Article
- Placental Malperfusion Is Associated With Adverse Outcomes in Congenital Heart Disease and With Genetic Variants in Placental Developmental Pathways.Journal of the American College of Cardiology · 2025Article
- Placental Pathological Findings and Clinical Outcomes in Triplet Pregnancies Conceived via Oocyte Donation and Non-Oocyte Donation: A Case-Control Study.Diagnostics (Basel, Switzerland) · 2025Article
- Evidence that atherosis of the spiral artery represents atherosclerotic lesions similar to those of native and transplant-induced atherosclerosis: implications for understanding the pathophysiology of obstetrical syndromes and long-term cardiovascular risk.American journal of obstetrics and gynecology · 2025Article
- Article
- Association of maternal asthma with congenital heart defects in offspring.Acta obstetricia et gynecologica Scandinavica · 2025Article
- "The significance of clinical foetal autopsy for reproductive health care: an ethical analysis in the German context".Medicine, health care, and philosophy · 2025Article
- From etiology to outcome: investigating the link between placental pathology and clinical risk for preterm birth and neurodevelopment.Pediatric research · 2025Article
- Machine Learning Assessment of Gestational Age in Accelerated Maturation, Delayed Maturation, Villous Edema, Chorangiosis, and Intrauterine Fetal Demise.Archives of pathology & laboratory medicine · 2025Article
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Authors and funding
12 authors at 10 institutions in 1 country.
Funding
Abstract
The importance of a fully functioning placenta for a good pregnancy outcome is unquestioned. Loss of function can lead to pregnancy complications and is often detected by a thorough placental pathologic examination. Placental pathology has advanced the science and practice of obstetrics and neonatal-perinatal medicine by classifying diseases according to underlying biology and specific patterns of injury. Many past obstacles have limited the incorporation of placental findings into both clinical studies and day-to-day practice. Limitations have included variability in the nomenclature used to describe placental lesions, a shortage of perinatal pathologists fully competent to analyze placental specimens, and a troubling lack of understanding of placental diagnoses by clinicians. However, the potential use of placental pathology for phenotypic classification, improved understanding of the biology of adverse pregnancy outcomes, the development of treatment and prevention, and patient counseling has never been greater. This review, written partly in response to a recent critique published in a major obstetrics-gynecology journal, reexamines the role of placental pathology by reviewing current concepts of biology; explaining the most recent terminology; emphasizing the usefulness of specific diagnoses for obstetrician-gynecologists, neonatologists, and patients; previewing upcoming changes in recommendations for placental submission; and suggesting future improvements. These improvements should include further consideration of overall healthcare costs, cost-effectiveness, the clinical value added of placental assessment, improvements in placental pathology education and practice, and leveraging of placental pathology to identify new biomarkers of disease and evaluate novel therapies tailored to specific clinicopathologic phenotypes of both women and infants.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.