Evidence map›Paper›PMID 35972967›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Identification of basal complex protein that is essential for maturation of transmission-stage malaria parasites.

Rebecca L Clements, Alexander A Morano, Francesca M Navarro, James P McGee, Esrah W Du, Vincent A Streva, Scott E Lindner, Jeffrey D Dvorin

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  12. Global Release of Translational Repression AcrossbioRxiv : the preprint server for biology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rebecca L ClementsBiological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115.ORCID 0000-0001-9726-1554
Alexander A MoranoBiological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115.
Francesca M NavarroBiological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115.
James P McGeeDivision of Infectious Diseases, Boston Children's Hospital, Boston, MA 02115.ORCID 0000-0003-0225-1172
Esrah W DuDivision of Infectious Diseases, Boston Children's Hospital, Boston, MA 02115.
Vincent A StrevaDivision of Infectious Diseases, Boston Children's Hospital, Boston, MA 02115.
Scott E LindnerDepartment of Biochemistry and Molecular Biology, the Huck Center for Malaria Research, Pennsylvania State University, University Park, PA 16802.ORCID 0000-0003-1799-3726
Jeffrey D DvorinDivision of Infectious Diseases, Boston Children's Hospital, Boston, MA 02115.ORCID 0000-0002-5883-7271

Funding

Functional investigation of a novel and essential subcellular compartment in Plasmodium falciparum transmission stage parasitesR01AI169648 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI JEFFREY D DVORIN · 2022 to 2026
$3.7M
Molecular mechanisms of schizogony in malaria parasitesR01AI145941 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI DVORIN, JEFFREY D · 2019 to 2023
$3.1M
Pediatric Infectious Diseases Research TrainingT32HD055148 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI WESSELS, MICHAEL R · 2008 to 2018
$2.7M
NIAID NIH HHS R01 AI145941NIAID NIH HHS R01 AI169648NICHD NIH HHS T32 HD055148
6 · The paper itself

Abstract

Malaria remains a global driver of morbidity and mortality. To generate new antimalarials, one must elucidate the fundamental cell biology of

Indexed as

GametogenesisMalaria, FalciparumPlasmodium falciparumProtozoan ProteinsAnimalsAntimalarialsDrug DesignAntimalarialsProtozoan Proteinsbasal complexmalariaPlasmodium falciparumtransmission

Identifiers

PMID35972967
PMCPMC9407223

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.