Evidence map›Paper›PMID 35972947›Full record

ArticlePloS one2022

Venous thromboembolic and hemorrhagic events after meningioma surgery: A single-center retrospective cohort study of risk factors.

Nebojsa Lasica, Djula Djilvesi, Vladimir Papic, Mladen Karan, Bojan Jelaca, Jagos Golubovic, Filip Pajicic, Milica Medic-Stojanoska, Petar Vulekovic, Lukas Rasulic

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Prevalence, characteristics, and risk factors of venous thromboembolism in patients with brain tumor undergoing craniotomy: a meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Pooled it
  2. Article
  3. Tumor treating fields alter local coagulation dynamics in glioblastoma patients.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Nebojsa LasicaClinic of Neurosurgery, Clinical Center of Vojvodina, Novi Sad, Serbia.
Djula DjilvesiClinic of Neurosurgery, Clinical Center of Vojvodina, Novi Sad, Serbia.
Vladimir PapicClinic of Neurosurgery, Clinical Center of Vojvodina, Novi Sad, Serbia.
Mladen KaranDepartment of Neurosurgery, Haukeland University Hospital, Bergen, Norway.
Bojan JelacaClinic of Neurosurgery, Clinical Center of Vojvodina, Novi Sad, Serbia.
Jagos GolubovicClinic of Neurosurgery, Clinical Center of Vojvodina, Novi Sad, Serbia.
Filip PajicicClinic of Neurosurgery, Clinical Center of Vojvodina, Novi Sad, Serbia.
Milica Medic-StojanoskaFaculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
Petar VulekovicClinic of Neurosurgery, Clinical Center of Vojvodina, Novi Sad, Serbia.
Lukas RasulicFaculty of Medicine, University of Belgrade, Belgrade, Serbia.ORCID 0000-0002-5674-0425
University of Novi Sad · RSHaukeland University Hospital · NOUniversity of Belgrade · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microsurgical resection of meningiomas in a majority of cases leads to a favorable outcome. Therefore, severe postoperative adverse events are less acceptable. The main purpose of this study was to investigate the incidence of symptomatic venous thromboembolism (VTE) and hemorrhagic complications in patients after operative treatment of intracranial meningiomas and to identify the risk factors in this patient subgroup. Of 106 patients undergoing elective craniotomy for meningioma overall incidence of symptomatic VTE was noted in 5.7% (six patients). For the risk-factor analysis older age (57.20 ± 11.60 vs. 71.00 ± 0.90 years, p < 0.001), higher body mass index (27.60 ± 4.80 vs. 33.16 ± 0.60 kg/m2, p < 0.001), WHO grade II (3.00% vs. 33.33%, p = 0.02), lower intraoperative blood loss (466.00 ± 383.70 vs. 216.70 ± 68.30 mL, p < 0.001), bedridden status and neurologic deficit (0.00% vs. 33.33%, p = 0.003 and 38.00% vs. 100.00%, p = 0.004) were associated with greater VTE risk. No risk factors for hemorrhagic complications were identified on univariate analysis. In conclusion, the incidence of VTE in meningioma patients is not negligible. Identified risk factors should be taken into account in the decision-making process for chemoprophylaxis when the risk of bleeding decreases.

Indexed as

Meningeal NeoplasmsMeningiomaVenous ThromboembolismHumansIncidencePostoperative ComplicationsRetrospective Studies

Identifiers

PMID35972947
PMCPMC9380925
OpenAlexW4291993870

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.