Evidence map›Paper›PMID 35972789›Full record

ArticleACS chemical biology2022

Understanding and Circumventing the Requirement for Native Thioester Substrates for α-Oxoamine Synthase Reactions.

Sarah E Ackenhusen, Ye Wang, Stephanie W Chun, Alison R H Narayan

Open access · greenAbstract read
In one paragraph

Article in ACS chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. JACS Au · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sarah E Ackenhusen
Ye Wang
Alison R H NarayanORCID 0000-0001-8290-0077
University of Michigan · US

Funding

Undergrad Supplement: Expanding the synthetic utility of natural product biosynthetic enzymesR35GM124880 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Alison Narayan · 2017 to 2026
$4.5M
Microfluidics in Biomedical Sciences Training ProgramT32EB005582 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FAN, XUDONG · 2005 to 2020
$3.9M
NIBIB NIH HHS T32 EB005582NIGMS NIH HHS R35 GM124880
6 · The paper itself

Abstract

Many enzyme classes require thioester electrophiles such as acyl-carrier proteins and acyl-coenzyme A substrates. For

Indexed as

Coenzyme APantetheineAcyl Carrier ProteinKineticsPhosphatesSubstrate SpecificityAcyl Carrier ProteinCoenzyme APantetheinePhosphates

Identifiers

PMID35972789
PMCPMC10082970
OpenAlexW4292183707

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.