Evidence map›Paper›PMID 35972592›Full record

Trial reportJournal of thrombosis and thrombolysis2022

Development and validation of a prediction model of catheter-related thrombosis in patients with cancer undergoing chemotherapy based on ultrasonography results and clinical information.

Shanhong Lin, Ning Zhu, YihanZhang, Liping Du, Shengmin Zhang

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of thrombosis and thrombolysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Development of a Machine Learning-Based Model for Predicting the Incidence of Peripheral Intravenous Catheter-Associated Phlebitis.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2024
    Article
  11. Article
  12. Article
  13. Predicting Catheter-Related Thrombosis in Colorectal Cancer Patients Using Clinical Features in 730 Patients.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shanhong LinDepartment of Ultrasound, Ningbo First Hospital, 59 Liuting Road, Ningbo, 315010, Zhejiang Province, People's Republic of China.
Ning ZhuDepartment of Respiratory and Critical Care Medicine, Ningbo First Hospital, Ningbo, People's Republic of China.
YihanZhangDepartment of Ultrasound, Ningbo First Hospital, 59 Liuting Road, Ningbo, 315010, Zhejiang Province, People's Republic of China.
Liping DuDepartment of Ultrasound, Ningbo First Hospital, 59 Liuting Road, Ningbo, 315010, Zhejiang Province, People's Republic of China.
Shengmin ZhangDepartment of Ultrasound, Ningbo First Hospital, 59 Liuting Road, Ningbo, 315010, Zhejiang Province, People's Republic of China. nbsmzhang@163.com.
Ningbo First Hospital · CN

Funding

Medical Science and Technology Project of Zhejiang Province 2022500148
6 · The paper itself

Abstract

Central venous catheters can be used conveniently to deliver medications and improve comfort in patients with cancer. However, they can cause major complications. The current study aimed to develop and validate an individualized nomogram for early prediction of the risk of catheter-related thrombosis (CRT) in patients with cancer receiving chemotherapy. In total, 647 patients were included in the analysis. They were randomly assigned to the training (n = 431) and validation (n = 216) cohorts. A nomogram for predicting the risk of CRT in the training cohort was developed based on logistic regression analysis results. The accuracy and discriminatory ability of the model were determined using area under the receiver operating characteristic curve (AUROC) values and calibration plots. Multivariate logistic regression analysis showed that body mass index, risk of cancer-related thrombosis, D-dimer level, and blood flow velocity were independent risk factors of CRT. The calibration plot showed an acceptable agreement between the predicted and actual probabilities of CRT. The AUROC values of the nomogram were 0.757 (95% confidence interval: 0.717-0.809) and 0.761 (95% confidence interval: 0.701-0.821) for the training and validation cohorts, respectively. Our model presents a novel, user-friendly tool for predicting the risk of CRT in patients with cancer receiving chemotherapy. Moreover, it can contribute to clinical decision-making.

Indexed as

NeoplasmsThrombosisCathetersHumansNomogramsUltrasonographyCancerCathetersChemotherapyNomogramPredictionThrombosis

Identifiers

PMID35972592
PMCPMC9553810
OpenAlexW4291991936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.