Evidence map›Paper›PMID 35972586›Full record

ArticleJournal of assisted reproduction and genetics2022

Recombinant human OVGP1 increases intracellular calcium and further potentiates the effects of progesterone on human sperm.

Sydney C Vanderkooi, Yuewen Zhao, Patricia D A Lima, Frederick W K Kan

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of assisted reproduction and genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Sydney C VanderkooiDepartment of Biomedical and Molecular Sciences, Faculty of Health Sciences, Queen's University, Kingston, Ontario, K7L 3N6, Canada.ORCID http://orcid.org/0000-0003-0478-9945
Yuewen ZhaoDepartment of Biomedical and Molecular Sciences, Faculty of Health Sciences, Queen's University, Kingston, Ontario, K7L 3N6, Canada.ORCID http://orcid.org/0000-0002-8765-1839
Patricia D A LimaQueen's CardioPulmonary Unit, Faculty of Health Sciences, Queen's University, Kingston, Ontario, K7L 3N6, Canada.ORCID http://orcid.org/0000-0002-6456-2470
Frederick W K KanDepartment of Biomedical and Molecular Sciences, Faculty of Health Sciences, Queen's University, Kingston, Ontario, K7L 3N6, Canada. kanfwk@queensu.ca.ORCID http://orcid.org/0000-0003-0026-9061
Queen's University · CA

Funding

CIHR Project Grant #PJT-162451
6 · The paper itself

Abstract

purposeTo investigate the effects of recombinant human oviduct-specific glycoprotein (rHuOVGP1) alone and in combination with progesterone (P4) on intracellular Ca

methodsFluorometric flow cytometry was performed to examine the effects of rHuOVGP1 on [Ca

resultsrHuOVGP1 increases [Ca

conclusionThe present study revealed that rHuOVGP1 may work with P4 to upregulate [Ca

Indexed as

CalciumProgesteroneCalcium ChannelsGlycoproteinsHumansMaleSemenSpermatozoaSperm CapacitationSperm MotilityTyrosineCalciumCalcium ChannelsGlycoproteinsOVGP1 protein, humanProgesteroneTyrosineHuman reproductionIn vitro fertilizationOviduct-specific glycoproteinProgesteroneSperm capacitation

Identifiers

PMID35972586
PMCPMC9596666
OpenAlexW4291916134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.