Evidence map›Paper›PMID 35972390›Full record

ArticleThe British journal of dermatology2022

Prevalence of skin sensitization and dermatitis among epoxy-exposed workers in the wind turbine industry.

Alexandra G Christiansen, Ole Carstensen, Mette Sommerlund, Per A Clausen, Jakob H Bønløkke, Vivi Schlünssen, Marléne Isaksson, Sigrun A J Schmidt, Henrik A Kolstad

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in The British journal of dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05891743 (Prevalence of Skin Sensitization and Dermatitis Among Epoxy-exposed Workers in the Wind Turbine Industry), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05891743 completednot on this mapstarted 2024, after this paper: background citation

Prevalence of Skin Sensitization and Dermatitis Among Epoxy-exposed Workers in the Wind Turbine Industry

TypeobservationalSponsorSiemens Gamesa Renewable Energy Blades, S.A.Ran2024 to 2024Enrolled126ConditionsDermatitisArmsPatch Test
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Alexandra G ChristiansenDepartment of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0003-1787-6669
Ole CarstensenDepartment of Occupational Medicine, The Regional Hospital Goedstrup, University Research Clinic, Herning, Denmark.
Mette SommerlundDepartment of Dermatology, Aarhus University Hospital, Aarhus, Denmark.
Per A ClausenNational Research Centre for the Working Environment, Copenhagen, Denmark.
Jakob H BønløkkeDepartment of Occupational and Environmental Medicine, Danish Ramazzini Centre, Aalborg University Hospital, Aalborg, Denmark.
Vivi SchlünssenNational Research Centre for the Working Environment, Copenhagen, Denmark.
Marléne IsakssonDepartment of Occupational and Environmental Dermatology, Lund University, Skane University Hospital Malmö, Malmö, Sweden.
Sigrun A J SchmidtDepartment of Dermatology, Aarhus University Hospital, Aarhus, Denmark.
Henrik A KolstadDepartment of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital, Aarhus, Denmark.
Aarhus University Hospital · DKAalborg University Hospital · DKAarhus University · DKLund University · SENational Research Centre for the Working Environment · DK

Funding

Siemens Gamesa Renewable EnergyThe Working Environment Research Fund 20175100924
6 · The paper itself

Abstract

backgroundA high prevalence of skin sensitization and dermatitis has been reported among workers exposed to epoxy components.

objectivesTo estimate the risk of skin sensitization and dermatitis among workers exposed to epoxy components during production of wind turbine blades while using comprehensive safety measures.

methodsA cross-sectional study of 180 highly epoxy-exposed production workers and 41 nonexposed office workers was conducted at two wind turbine blade factories in Denmark. Participants underwent a skin examination, were tested with a tailored patch test panel including epoxy-containing products used at the factories, and answered a questionnaire.

resultsSixteen production workers (8·9%) were sensitized to an epoxy component compared with none of the office workers. Skin sensitization was more frequent within the first year of exposed employment. Strong selection bias by atopic status was indicated. Among nonatopic workers, the prevalence of dermatitis was higher among production workers (16·4%) than among office workers [6·5%, odds ratio (OR) 2·3, 95% confidence interval (CI) 0·6-9·1] and higher among the sensitized workers (43·8%) than the nonsensitized workers (14·6%, OR 4·5, 95% CI 1·6-12·7). Resins based on diglycidyl ether of bisphenol A and F were the most frequent sensitizers. One of the four workers sensitized to epoxy components used at the factories did not react to the epoxy resin of the TRUE test

conclusionsDespite comprehensive skin protection, sensitization and dermatitis are prevalent among highly epoxy-exposed workers in the wind turbine industry in Denmark. Our findings document the need for intensified preventive efforts and emphasize the importance of tailored patch testing. What is already known about this topic? Epoxy components are well-known sensitizers of the skin. A high prevalence of skin sensitization and dermatitis has been reported among workers exposed to epoxy components. Comprehensive protective equipment is recommended when working with epoxy components. What does this study add? Despite comprehensive skin protection, skin sensitization and dermatitis are prevalent among epoxy-exposed workers. We found that 40% of workers sensitized to epoxy products had dermatitis. Only 75% of the sensitized workers were detected by the epoxy resin of the TRUE test

Indexed as

Dermatitis, Allergic ContactDermatitis, OccupationalCross-Sectional StudiesEpoxy ResinsHumansPatch TestsPrevalenceEpoxy Resins

Identifiers

PMID35972390
PMCPMC10087335
OpenAlexW4291992235

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.