Evidence map›Paper›PMID 35972301›Full record

Trial reportAnales del sistema sanitario de Navarra2022

[Effectiveness on adherence to biological drugs and experience of a pharmaceutical intervention based on CMO model in patients with rheumatic disease (AdhER-2 study)].

A Caso-González, J Núñez-Rodríguez, Y González-Pérez, C Leralta-González, V Sanz-Alonso, C Obaldia-Alaña

Open access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Anales del sistema sanitario de Navarra, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. [Health-System Pharmacy services for outpatients are evolving].Anales del sistema sanitario de Navarra · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

A Caso-GonzálezServicio de Farmacia. Hospital San Pedro. Logroño (La Rioja). España. alicia.caso@usal.es.
J Núñez-RodríguezServicio de Farmacia. Hospital San Pedro. Logroño (La Rioja). España. Jessica_nr92@hotmail.com.
Y González-PérezServicio de Farmacia. Hospital San Pedro. Logroño (La Rioja). España. yaredgpz@gmail.com.
C Leralta-GonzálezServicio de Farmacia. Hospital San Pedro. Logroño (La Rioja). España. cleralta@riojasalud.es.
V Sanz-AlonsoServicio de Farmacia. Hospital San Pedro. Logroño (La Rioja). España. vsalonso@riojasalud.es.
C Obaldia-AlañaServicio de Farmacia. Hospital San Pedro. Logroño (La Rioja). España. mcobaldia@riojasalud.es.
Hospital San Pedro · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to assess the effectiveness on adherence to treatment with biologic disease modifying anti-rheumatic drugs (b-DMARD) and experience with providers of healthcare of a CMO pharmaceutical intervention care model in subjects with rheu-matoid arthritis, psoriatic arthritis, and ankylosing spondylitis stratified according to their needs.

methodProspective, single-centre randomized controlled study. The study period was eleven months. Non-compliant patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondy-litis treated with b-DMARD were included. Patients were randomized to a control (CG) or intervention group (IG) who received regular or the CMO pharmaceutical intervention model treatment, respec-tively. Baseline and final adherence were determined using medication possession ratio, the Compliance Questionnaire on Rheu-matology, and Morisky Medication Adherence Scale. To assess baseline and final patient experience with providers of healthcare we applied the Chronic Patient Experience Assessment Instrument (IEXPAC).

resultsFor the IG, one patient (5.6%) was categorized as priority 1, nine (50.0%) as priority 2, and eight (44.4%) as priority 3. Ninety pharmaceutical interventions were carried out (5.1±1.8 interventions / patient). At the end of the study, the IG showed higher fre-quency of patients who adhered to the pharmaceutical intervention (77.8 vs 18.8%; p=0.002) and higher mean IEXPAC score (7.6±1.3 vs 5.8±1.1; p <0.001) in comparison to the CG. Conclusion The CMO pharmaceutical intervention model significantly improves patient adherence to b-DMARD and their experience with the providers of healthcare.

Indexed as

Antirheumatic AgentsArthritis, PsoriaticArthritis, RheumatoidBiological ProductsHumansPharmaceutical PreparationsProspective StudiesAntirheumatic AgentsBiological ProductsPharmaceutical Preparations

Identifiers

PMID35972301
PMCPMC10130795
OpenAlexW4291964170

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.