ArticleAnnals of botany2022
Network of the transcriptome and metabolomics reveals a novel regulation of drought resistance during germination in wheat.
Article in Annals of botany, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- GhDREB1B-GhFAD3-2 module mediates drought tolerance by regulating linolenic acid biosynthesis in cotton.Science China. Life sciences · 2026Article
- Metabolic response strategies of spring wheat under osmotic stress.Frontiers in plant science · 2026Article
- Metabolome integrated with transcriptome, and genome analysis revealed higher accumulations of phytoalexins enhance resistance against Magnaporthe oryzae in new Zhefang rice variety diantun 506.BMC plant biology · 2025Article
- Screening and Identification of Drought-Tolerant Genes in Tomato (Plants (Basel, Switzerland) · 2025Article
- Weighted Gene Co-Expression Network Analysis Uncovers Core Drought Responsive Genes in Pecan (Plants (Basel, Switzerland) · 2025Article
- Review
- Metabolomic and transcriptomic analyses of drought resistance mechanisms in sorghum varieties.PeerJ · 2025Article
- Exploring Drought Resistance Genes from the Roots of the Wheat Cultivar Yunhan1818.International journal of molecular sciences · 2024Article
- Metabolomics combined with transcriptomics and physiology reveals the regulatory responses of soybean plants to drought stress.Frontiers in genetics · 2024Article
- Metabolomic and transcriptomic responses of Adiantum (Frontiers in genetics · 2023Article
- Multi-Omics Uncover the Mechanism of Wheat under Heavy Metal Stress.International journal of molecular sciences · 2022Review
- Different adaptive patterns of wheat with different drought tolerance under drought stresses and rehydration revealed by integrated metabolomic and transcriptomic analysis.Frontiers in plant science · 2022Article
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10 authors.
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Abstract
BACKGROUND AND
aimsThe North China Plain, the highest winter-wheat-producing region of China, is seriously threatened by drought. Traditional irrigation wastes a significant amount of water during the sowing season. Therefore, it is necessary to study the drought resistance of wheat during germination to maintain agricultural ecological security. From several main cultivars in the North China Plain, we screened the drought-resistant cultivar JM47 and drought-sensitive cultivar AK58 during germination using the polyethylene glycol (PEG) drought simulation method. An integrated analysis of the transcriptome and metabolomics was performed to understand the regulatory networks related to drought resistance in wheat germination and verify key regulatory genes.
methodsTranscriptional and metabolic changes were investigated using statistical analyses and gene-metabolite correlation networks. Transcript and metabolite profiles were obtained through high-throughput RNA-sequencing data analysis and ultra-performance liquid chromatography quadrupole time-of-flight tandem mass spectrometry, respectively. KEY
resultsA total of 8083 and 2911 differentially expressed genes (DEGs) and 173 and 148 differential metabolites were identified in AK58 and JM47, respectively, under drought stress. According to the integrated analysis results, mammalian target of rapamycin (mTOR) signalling was prominently enriched in JM47. A decrease in α-linolenic acid content was consistent with the performance of DEGs involved in jasmonic acid biosynthesis in the two cultivars under drought stress. Abscisic acid (ABA) content decreased more in JM47 than in AK58, and linoleic acid content decreased in AK58 but increased in JM47. α-Tocotrienol was upregulated and strongly correlated with α-linolenic acid metabolism.
conclusionsThe DEGs that participated in the mTOR and α-linolenic acid metabolism pathways were considered candidate DEGs related to drought resistance and the key metabolites α-tocotrienol, linoleic acid and l-leucine, which could trigger a comprehensive and systemic effect on drought resistance during germination by activating mTOR-ABA signalling and the interaction of various hormones.
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