Evidence map›Paper›PMID 35972202›Full record

ArticleAnalytical chemistry2022

SCORe: SARS-CoV-2 Omicron Variant RBD-Binding DNA Aptamer for Multiplexed Rapid Detection and Pseudovirus Neutralization.

Lucy F Yang, Nataly Kacherovsky, Joey Liang, Stephen J Salipante, Suzie H Pun

Abstract read
In one paragraph

Article in Analytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Aptamers 101: aptamer discovery andChemical science · 2023
    Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lucy F YangDepartment of Bioengineering, University of Washington, Seattle, Washington 98195, United States.
Nataly KacherovskyDepartment of Bioengineering, University of Washington, Seattle, Washington 98195, United States.
Joey LiangDepartment of Bioengineering, University of Washington, Seattle, Washington 98195, United States.
Stephen J SalipanteDepartment of Laboratory Medicine, University of Washington, Seattle, Washington 98195, United States.
Suzie H PunDepartment of Bioengineering, University of Washington, Seattle, Washington 98195, United States.ORCID 0000-0003-1443-4996

Funding

RADx-Rad Discoveries & Data: Consortium Coordination Center Program OrganizationU24LM013755 · NLM · YALE UNIVERSITY · PI ARONOFF-SPENCER, ELIAH S, OHNO-MACHADO, LUCILA · 2021 to 2023
$23.3M
Touchscreen-compatible, real-time electrochemical sensing of SARS-CoV-2U01AA029316 · NIAAA · UNIVERSITY OF WASHINGTON · PI PUN, SUZIE H., SMITH, JOSHUA R · 2021 to 2022
$922k
NIAAA NIH HHS U01 AA029316NLM NIH HHS U24 LM013755
6 · The paper itself

Abstract

During the COVID-19 (coronavirus disease 2019) pandemic, several SARS-CoV-2 variants of concern emerged, including the Omicron variant, which has enhanced infectivity and immune invasion. Many antibodies and aptamers that bind the spike (S) of previous strains of SARS-CoV-2 either do not bind or bind with low affinity to Omicron S. In this study, we report a high-affinity

Indexed as

Aptamers, NucleotideCOVID-19RNA VirusesAngiotensin-Converting Enzyme 2Antibodies, ViralHumansSARS-CoV-2Angiotensin-Converting Enzyme 2Antibodies, ViralAptamers, Nucleotide

Identifiers

PMID35972202
PMCPMC9397568

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.