Evidence map›Paper›PMID 35972192›Full record

SynthesisBiochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology2022

Teaching genomics to life science undergraduates using cloud computing platforms with open datasets.

Toryn M Poolman, Andrea Townsend-Nicholson, Amanda Cain

Open access · hybridAbstract readMeta-Analysis
In one paragraph

Synthesis in Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Teaching genomics to life science undergraduates using cloud computing platforms with open datasets.Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology · 2022
    Pooled it
  2. Article
  3. Teaching Medical Students to Use Supercomputers: A Personal Reflection.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  4. Automated management of AWS instances for training.GigaByte (Hong Kong, China) · 2024
    Article
  5. Breaking Barriers in Large Classes: Using Cloud Computing and Computational Biology to Implement Research-Inspired Curricula in Biochemistry I.Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Toryn M PoolmanStructural & Molecular Biology Faculty of Life Sciences, UCL, London, UK.ORCID 0000-0002-7427-6603
Andrea Townsend-NicholsonStructural & Molecular Biology Faculty of Life Sciences, UCL, London, UK.ORCID 0000-0002-7250-2208
Amanda CainStructural & Molecular Biology Faculty of Life Sciences, UCL, London, UK.
Institute of Structural and Molecular Biology · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The final year of a biochemistry degree is usually a time to experience research. However, laboratory-based research projects were not possible during COVID-19. Instead, we used open datasets to provide computational research projects in metagenomics to biochemistry undergraduates (80 students with limited computing experience). We aimed to give the students a chance to explore any dataset, rather than use a small number of artificial datasets (~60 published datasets were used). To achieve this, we utilized Google Colaboratory (Colab), a virtual computing environment. Colab was used as a framework to retrieve raw sequencing data (analyzed with QIIME2) and generate visualizations. Setting up the environment requires no prior experience; all students have the same drive structure and notebooks can be shared (for synchronous sessions). We also used the platform to combine multiple datasets, perform a meta-analysis, and allowed the students to analyze large datasets with 1000s of subjects and factors. Projects that required increased computational resources were integrated with Google Cloud Compute. In future, all research projects can include some aspects of reanalyzing public data, providing students with data science experience. Colab is also an excellent environment in which to develop data skills in multiple languages (e.g., Perl, Python, Julia).

Indexed as

Cloud ComputingCOVID-19GenomicsHumansSoftwareStudentsBioinformaticsGoogle ColabMicrobiomeQIIME2

Identifiers

PMID35972192
PMCPMC9804627
OpenAlexW4291972670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.