Evidence map›Paper›PMID 35972021›Full record

ArticleEmerging microbes & infections2022

Ultrasensitive and rapid identification of ESRI developer- and piperacillin/tazobactam-resistant

Angel Rodríguez Villodres, Lydia Gálvez Benítez, Manuel J Arroyo, Gema Méndez, Luis Mancera, Andrea Vila Domínguez, José Antonio Lepe Jímenez, Younes Smani

Open access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Angel Rodríguez VillodresClinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Virgen del Rocío University Hospital, Seville, Spain.
Lydia Gálvez BenítezClinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Virgen del Rocío University Hospital, Seville, Spain.
Manuel J ArroyoClover Bioanalytical Software, Av. del Conocimiento, 41, 18016 Granada, Spain.
Gema MéndezClover Bioanalytical Software, Av. del Conocimiento, 41, 18016 Granada, Spain.
Luis ManceraClover Bioanalytical Software, Av. del Conocimiento, 41, 18016 Granada, Spain.
Andrea Vila DomínguezClinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Virgen del Rocío University Hospital, Seville, Spain.
José Antonio Lepe JímenezClinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Virgen del Rocío University Hospital, Seville, Spain.
Younes SmaniClinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Virgen del Rocío University Hospital, Seville, Spain.ORCID 0000-0001-9302-8384
Instituto de Biomedicina de Sevilla · ESSoftware (Spain) · ESCentro Andaluz de Biología del Desarrollo · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe excessive use of piperacillin/tazobactam (P/T) has promoted the emergence of P/T-resistant

methodsWe used automated Clover MS Data Analysis software to analyse the protein profile spectra obtained by MALDI-MS from a collection of 248

resultsWe demonstrated that MALDIpiptaz can efficiently and rapidly (15 min) discriminate between P/T-resistant, ESRI developer and P/T-susceptible isolates and allowed the correct classification between ESRI developers from their isogenic resistance to P/T.

conclusionThe combination of excellent performance and cost-effectiveness are all desirable attributes, allowing the MALDIpiptaz test to be a useful tool for the rapid determination of P/T resistance in clinically relevant

Indexed as

Escherichia coliEscherichia coli InfectionsAnti-Bacterial Agentsbeta-LactamasesHumansMicrobial Sensitivity TestsPiperacillin, Tazobactam Drug CombinationAnti-Bacterial Agentsbeta-LactamasesPiperacillin, Tazobactam Drug Combinationalgorithmbeta-lactamasebeta-lactamase inhibitorEscherichia colimachine learningPiperacillinresistancetazobactam

Identifiers

PMID35972021
PMCPMC9423838
OpenAlexW4291954679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.